We investigated the focal characteristics of open-regional cylindrical microlens arrays with long focal depth by using a rigorous boundary-element method (BEM) and three scalar methods, i.e., a Kirchhoff and two Rayleigh-Sommerfeld diffraction integral forms. Numerical analysis clearly shows that the model cylindrical microlens arrays with different f-numbers can generate focusing beams with both long focal depth and high transverse resolution. The performance of the cylindrical microlens arrays, such as extended focal depth, relative extended focal depth, diffraction efficiency, and focal spot size, is appraised and analyzed. From a comparison of the results obtained by the rigorous BEM and by scalar approximations, we found that the results are quite similar when the f-number equals f/1.6; however, they are quite different for f/0.8. We conclude that the BEM should be adopted to analyze the performance of a microlens array system whose f-number is less than f/1.0.
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http://dx.doi.org/10.1364/ao.43.005183 | DOI Listing |
J Appl Oral Sci
January 2025
Nanjing University, Research Institute of Stomatology, Affiliated Hospital of Medical School, Nanjing Stomatological Hospital, Department of Oral and Maxillofacial Trauma Orthognathic Plastic Surgery, Nanjing, China.
Objectives: Depth of invasion (DOI) in oral squamous cell carcinoma (OSCC) guides treatment and prognosis but lacks three-dimensional (3D) insight. Thus, this study aimed to investigate the feasibility and accuracy of Lugol's iodine-enhanced micro-computed tomography (CT) for the 3D measurement of DOI in OSCC samples.
Methodology: In total, 50 in vitro OSCC samples from Nanjing Stomatological Hospital (July 2022 to January 2024) were subjected to micro-CT imaging with a slice thickness of 50 μm following 3% Lugol iodine staining for 12 h, followed by pathological examination and staining.
Front Plant Sci
December 2024
School of Future Technology, Fujian Agriculture and Forestry University, Fuzhou, China.
In the cultivation of green chili peppers, the similarity between the fruit and background color, along with severe occlusion between fruits and leaves, significantly reduces the efficiency of harvesting robots. While increasing model depth can enhance detection accuracy, complex models are often difficult to deploy on low-cost agricultural devices. This paper presents an improved lightweight Pepper-YOLO model based on YOLOv8n-Pose, designed for simultaneous detection of green chili peppers and picking points.
View Article and Find Full Text PDFBioact Mater
April 2025
School of Life Science, Advanced Research Institute of Multidisciplinary Science, Aerospace Center Hospital, Key Laboratory of Molecular Medicine and Biotherapy, Key Laboratory of Medical Molecule Science and Pharmaceutics Engineering, Beijing Institute of Technology, Beijing, 100081, China.
Immune checkpoint blockade (ICB) therapy is a widely favored anti-tumor treatment, but it shows limited response to non-immunogenic "cold" tumors and suffers from drug resistance. Photodynamic therapy (PDT), as a powerful localized treatment approach, can convert a "cold tumor" into a "hot tumor" by inducing immunogenic cell death (ICD) in tumor cells, thereby enhancing tumor immunogenicity and promoting tumor immunotherapy. However, the effectiveness of PDT is largely hindered by the limited penetration depth into tumor tissues.
View Article and Find Full Text PDFNat Commun
January 2025
Department of Pharmacology, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Cortical interneurons generated from ganglionic eminence via a long-distance journey of tangential migration display evident cellular and molecular differences across brain regions, which seeds the heterogeneous cortical circuitry in primates. However, whether such regional specifications in interneurons are intrinsically encoded or gained through interactions with the local milieu remains elusive. Here, we recruit 685,692 interneurons from cerebral cortex and subcortex including ganglionic eminence within the developing human and macaque species.
View Article and Find Full Text PDFClin Oral Investig
January 2025
Clinic of Conservative and Preventive Dentistry, Center for Dental Medicine, University of Zurich, Zurich, Switzerland.
Objective: Aim of this study was to critically appraise clinical evidence on the potential benefits of adjunctive use of superfoods green tea and turmeric as mouthrinse or local delivery agents in the treatment of periodontal disease.
Materials And Methods: Electronic searches were performed in four databases for randomized trials from inception to February 2024 assessing the supplemental use of superfoods green tea and turmeric for gingivitis/periodontitis treatment. After duplicate study selection, data extraction, and risk-of-bias assessment with the RoB 2 tool, random-effects meta-analyses of Mean Differences (MD) or Standardized Mean Differences (SMD) with their 95% confidence intervals (CI) were performed.
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