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Beta papillomaviruses: From foe to friend in skin cancer immunity.
Cancer Cell
December 2024
Pre-Cancer Immunology Laboratory, University College London Cancer Institute, Paul O'Gorman Building, 72 Huntley Street, London WC1E 6BT, UK; Cancer Research UK Lung Cancer Centre of Excellence. Electronic address:
In this issue of Cancer Cell, Son et al. highlight an unexpected role for skin β-papillomaviruses in the protection against skin carcinogenesis. T cell immunity to skin papillomaviruses blocks the expansion of p53 mutant clones in ultraviolet (UV) radiation-damaged skin, preventing the development of skin cancer.
View Article and Find Full Text PDFEfferocytosis: The Janus-Faced Gatekeeper of Aging and Tumor Fate.
Aging Cell
January 2025
Department of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
From embryogenesis to aging, billions of cells perish daily in mammals. The multistep process by which phagocytes engulf these deceased cells without eliciting an inflammatory response is called efferocytosis. Despite significant insights into the fundamental mechanisms of efferocytosis, its implications in disorders such as aging and cancer remain elusive.
View Article and Find Full Text PDFPeer review comments: Friend or foe?
J Am Assoc Nurse Pract
January 2025
College of Graduate Nursing, Western University of Health Sciences, Pomona, California.
Peer review is a time-honored cornerstone of publishing. Peer reviewers, often blinded to the author, provide feedback to clarify the manuscript and validate the key messages and sciences. Authors may openly accept the feedback outright and make revisions.
View Article and Find Full Text PDFof chickens: the changing face of an old foe.
Avian Pathol
January 2025
Pathobiology and Population Sciences, Royal Veterinary College, North Mymms, UK.
The cost of coccidiosis in chickens fluctuates considerably, peaking in 2022.Three new species can infect chickens and escape current vaccines. infection exerts wide-ranging effects on enteric microbiota.
View Article and Find Full Text PDFThe role of SGK1 in neurologic diseases: A friend or foe?
IBRO Neurosci Rep
December 2024
Department of Biotechnology, Basic Medical School, Guangdong Medical University, Dongguan 523808, China.
Serum and glucocorticoid-regulated kinase 1 (SGK1), a member of the AGC family of serine/threonine protein kinases, is one of the most conserved protein kinases in eukaryotic evolution. SGK1 is expressed to varying degrees in various types of cells throughout the body, and plays an important role in hypertension, ion channels, oxidative stress, neurological disorders, and cardiovascular regulation. In recent years, a number of scholars have devoted themselves to the study of the role and function of SGK1 in neurological diseases.
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