[Association of hereditary hemochromatosis and pernicious anaemia].

Rev Med Interne

Service de médecine interne, CHR Pellegrin, place Raba-Léon, 33000 Bordeaux, France.

Published: October 2004

Introduction: Hereditary hemochromatosis is inherited as an autosomal recessive trait. It is characterized by increased absorption of dietary iron. The association between pernicious anaemia and hereditary hemochromatosis has never been described.

Exegesis: We report a case of paradoxical association of hereditary hemochromatosis and pernicious anaemia.

Conclusion: It seems that pernicious anaemia may prevent manifestations of hemochromatosis. We suppose that this protective role is due to atrophic body gastritis with iron malabsorption.

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http://dx.doi.org/10.1016/j.revmed.2004.07.001DOI Listing

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