We report preoperative virtual images reconstructed from three-dimensional fast advanced spin echo (3D-FASE)and evaluate the cause of a trigeminal neuralgia due to an epidermoid tumor. A 60-year-old man had a 3-year-history of atypical trigeminal neuralgia in the left V2 region accompanied by a hypesthesia in the cheek. Neuroimaging demonstrated an epidermoid tumor in the left cerebello-pontine cistern. As the preoperative virtual images reconstructed from 3D-FASE images indicated that the superior cerebellar artery compressed the trigeminal nerve at the root entry zone, we carried out total removal of the tumor and microvascular decompression of the trigeminal nerve. It was possible to visualize the fine structures around the trigeminal nerve, because an epidermoid tumor shows a high intensity mass on 3D-FASE images. The simulated 3D images were useful in deciding upon the additional microvascular decompression surgery for trigeminal neuralgia after total removal of the epidermoid tumor.
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http://dx.doi.org/10.7888/juoeh.26.295 | DOI Listing |
Med J Armed Forces India
December 2024
SSMO Neurosurgery, YCM Hospital & PGI, Pimpri, Pune, India.
Intracranial epidermoid cyst (EC) is a slow-growing, benign lesion that rarely undergoes a malignant transformation. When it does occur, the clinical course is aggressive. Certain radiological criteria may give a clue to diagnosis and help in deciding the appropriate course of action as well as prognostication.
View Article and Find Full Text PDFJpn J Radiol
December 2024
Department of Diagnostic Imaging and Nuclear Medicine, Graduate School of Medicine, Kyoto University, 54 Shogoin Kawaharacho, Kyoto, 6068507, Japan.
Purpose: To compare quantitative values and image quality between single-shot echo-planar imaging (SS-EPI) diffusion-weighted imaging (DWI) and two-dimensional turbo gradient- and spin-echo DWI with non-Cartesian BLADE trajectory (TGSE-BLADE DWI) in patients with epidermoid cyst.
Methods: Patients with epidermoid cyst who underwent both SS-EPI DWI and TGSE-BLADE DWI were included in this study. Two raters placed ROIs encircling the entire epidermoid cyst on SS-EPI DWI, and then on TGSE-BLADE DWI.
Discov Oncol
December 2024
School of Pharmacy, Shaoyang University, Shaoyang, 422000, Hunan, China.
Lung adenocarcinoma (LUAD) represents one of the most common subtypes of lung cancer with high rates of incidence and mortality, which contributes to substantial health and economic demand across the globe. Treatment today mainly consists of surgery, radiotherapy, and chemotherapy, but their efficacy in advanced stages is often suboptimal and emphasizes the clear need for new biomarkers and therapeutic targets. Using comprehensive bioinformatics analyses consisting of the Cancer Genome Atlas (TCGA), Gene Expression Omnibus (GEO), Human Protein Atlas (HPA) and Clinical Proteomic Tumor Analysis Consortium (CPTAC), immune infiltration analysis and functional enrichment analysis, and single-cell analysis, we examined the potential of keratin 18 (KRT18) as a candidate biomarker in advanced LUAD.
View Article and Find Full Text PDFJ Funct Biomater
December 2024
Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino 142290, Russia.
X-ray-induced photodynamic therapy (X-PDT) represents a promising new method of cancer treatment. A novel type of nanoscintillator based on cerium fluoride (CeF) nanoparticles (NPs) modified with flavin mononucleotide (FMN) has been proposed. A method for synthesizing CeF-FMN NPs has been developed, enabling the production of colloidal, spherical NPs with an approximate diameter of 100 nm, low polydispersity, and a high fluorescence quantum yield of 0.
View Article and Find Full Text PDFCurr Issues Mol Biol
December 2024
Department of Biophysics, Institute of Biology and Biomedicine, Lobachevsky State University of Nizhny Novgorod, 23 Gagarin Ave., 603022 Nizhny Novgorod, Russia.
Modern radiotherapy utilizes a broad range of sources of ionizing radiation, both low-dose-rate (LDR) and high-dose-rate (HDR). However, the mechanisms underlying specific dose-rate effects remain unclear, especially for corpuscular radiation. To address this issue, we have irradiated human epidermoid carcinoma A431 cells under LDR and HDR regimes.
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