The authors present the first Polish case of an extremely rare thymoma in a 70-year old female surgical patient with 15-year observation before surgery.
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Hide-and-Seek With Spindle-Cell-Component-Poor Metaplastic Thymoma.
Cureus
May 2024
National Center of Pathology, Vilnius University Hospital Santaros Klinikos, Vilnius, LTU.
Metaplastic thymoma is a rare biphasic thymic tumor with indolent behavior and recurrent gene rearrangement. Although the diagnosis of this tumor is usually straightforward based on hematoxylin and eosin (H&E) findings alone, cases with scant spindle-cell ("pseudosarcomatous stroma") components can be easily confused with more commonly occurring type A thymoma. We present a case of metaplastic thymoma with a sparse stroma-like spindle-cell component, discussing its histological and immunohistochemical hints and drawing attention to the visual similarity to type A thymoma.
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Pol J Pathol
November 2004
Department of Clinical and Experimental Pathomorphology, Collegium Medicum, Jagiellonian University, Kraków.
The authors present the first Polish case of an extremely rare thymoma in a 70-year old female surgical patient with 15-year observation before surgery.
View Article and Find Full Text PDFThymoma with pseudosarcomatous stroma.
Yonsei Med J
October 2001
Department of Pathology, Yonsei University College of Medicine, C.P.O. Box 8044, Seoul 120-752, Korea.
Thymoma with psuedosarcomatous stroma is a recently described, rare variant of thymomas that are characterized by having a biphasic histologic pattern which consists of both an epithelial and a spindle cell stromal component. So far only 11 cases having similar histologic findings have been reported worldwide. At this time we report a case of this rare variant of thymoma which occurred in a 53-year-old Korean man.
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Ann Med
October 1999
Department of Pathology, University of Würzburg, Germany.
A WHO committee recently defined criteria for distinguishing between thymic epithelial tumours (TET) and classified them as type A, AB, B1-3 and C thymomas. As the terminology for each WHO type is still controversial, it is recommended to use also other names in addition to the WHO classification to allow comparability of future clinicopathological studies. We consider type A and AB thymomas (medullary and mixed thymomas) clinically benign, whereas type B1-3 thymomas (predominantly cortical and cortical thymomas and well-differentiated thymic carcinomas) are of low-grade malignant potential and most type C thymomas (category II malignant thymomas) are highly malignant.
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Pathol Res Pract
November 1999
Institute of Pathology, University of Würzburg, Germany.
A group of biphasic low-grade thymic epithelial tumors is presented that we suggest calling low-grade metaplastic carcinoma of the thymus [37]. Four of the patients were men, their age ranging from 44 to 71 years. Three tumors invaded mediastinal fat or pleura.
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