This study of 7,139 U.S. coal miners used linear regression analysis to relate estimates of cumulative dust exposure to several pulmonary function variables measured during medical examinations undertaken between 1969 and 1971. The exposure data included newly derived cumulative dust exposure estimates for the period up to time of examination based on large data bases of underground airborne dust sampling measurements. Negative associations were found between measures of cumulative exposure and FEV1, FVC, and the FEV1/FVC ratio (p less than 0.001). In general, the relationships were similar to those reported for British coal miners. Overall, the results demonstrate an adverse effect of coal mine dust exposure on pulmonary function that occurs even in the absence of radiographically detected pneumoconiosis.
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http://dx.doi.org/10.1164/ajrccm/145.3.605 | DOI Listing |
Indian J Occup Environ Med
December 2024
Department of Industrial Hygiene and Toxicology, ICMR-Regional Occupational Health Centre (S), NIOH, ICMR Complex, Bengaluru, Karnataka, India.
Background: Beedi rolling is a labor-intensive occupation that can cause a variety of health problems due to prolonged exposure to tobacco dust. This cross-sectional study aimed to assess morbidity, hematological profile, and DNA damage among beedi rollers in Karnataka.
Methods: A total of 153 participants, including 85 beedi and 65 non-beedi rollers, were enrolled in the study.
Trop Biomed
December 2024
Division of Biomedical Sciences, School of Pharmacy, University of Nottingham Malaysia, 43500, Semenyih, Malaysia.
House Dust Mites (HDMs) like Dermatophagoides farinae (D. farinae), Dermatophagoides pteronyssinus (D. pteronyssinus) and Blomia tropicalis (B.
View Article and Find Full Text PDFRespir Res
January 2025
Department of Respiratory Medicine, Laboratory for Translational Research in Obstructive Pulmonary Diseases, Medical Research Building (MRB) II, Ghent University Hospital, 2 Floor, Corneel Heymanslaan 10, 9000, Ghent, Belgium.
Introduction: Diesel exhaust particles (DEP) have been proven to aggravate asthma pathogenesis. We previously demonstrated that concurrent exposure to house dust mite (HDM) and DEP in mice increases both eosinophils and neutrophils in bronchoalveolar lavage fluid (BALF) and also results in higher levels of neutrophil-recruiting chemokines and neutrophil extracellular trap (NET) formation compared to sole HDM, sole DEP or saline exposure. We aimed to evaluate whether treatment with anti-IL-5 can alleviate the asthmatic features in this mixed granulocytic asthma model.
View Article and Find Full Text PDFBMC Public Health
January 2025
School of Public Health, General Hospital of Ningxia Medical University, Ningxia Medical University, Yinchuan, Ningxia, 750004, People's Republic of China.
Background: Mental health issues, particularly anxiety and depression, are increasingly prevalent among the occupational population. Environmental factors, such as dust exposure, may contribute to the worsening of these symptoms. While previous studies have examined the association between dust exposure and mental health, the moderating effect of sleep duration on this link in occupational settings remains under-explored.
View Article and Find Full Text PDFEnviron Sci Technol
January 2025
Institute of Nuclear Agricultural Sciences, Key Laboratory of Nuclear Agricultural Sciences of Ministry of Agriculture of PRC, Zhejiang University, Hangzhou 310058, China.
Decabromodiphenyl ethane (DBDPE), a key alternative to deca-BDE (BDE-209), has been ubiquitous in the receiving ecosystem. However, little is known about its uptake process and fate in plants. Here, the plant absorption, distribution, and metabolism of C-DBDPE under two distinct exposure pathways (i.
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