The production of protective neutralizing antibodies occurs quickly in some viral infections but very slowly in others. In a new study, surface glycoproteins (the targets of neutralization) of 2 different viruses were genetically switched. Analysis of the neutralizing antibody response to each of the 2 parent and recombinant viruses in infected mice revealed that the speed of neutralizing antibody induction was intrinsically dependent on the surface glycoprotein and not the rest of the virus.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC518670 | PMC |
| http://dx.doi.org/10.1172/JCI23098 | DOI Listing |
Publication Analysis
Top Keywords
neutralizing antibody
8
judging virus
4
virus cover
4
cover production
4
production protective
4
protective neutralizing
4
neutralizing antibodies
4
antibodies occurs
4
occurs viral
4
viral infections
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!