Twenty-two cases of pulmonary plasmacytoma have been reported in the literature and verified by immunohistochemistry or other diagnostic tests. The treatment for this rare tumor has included various combinations of surgical resection, chemotherapy, and radiation therapy. We report a case of a middle-age man who underwent endoscopic debulking followed by laser ablation for a pulmonary plasmacytoma, which showed a prominent endobronchial location with clinical and histopathologic verification.
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Solitary extramedullary plasmacytoma in the hilar region: A case of minimal marrow involvement in an elderly male.
Int J Surg Case Rep
January 2025
Department of Pathology, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India. Electronic address:
Introduction And Importance: Solitary extramedullary plasmacytoma (SEP) is a rare plasma cell neoplasm, constituting around 3 % of plasma cell malignancies. SEP typically presents as a single tumor, either in bone or soft tissue, without systemic disease, and is often misdiagnosed due to its nonspecific symptoms. Diagnosis requires biopsy and extensive imaging studies to exclude multiple myeloma and other malignancies.
View Article and Find Full Text PDFPrimary pulmonary plasmacytoma: A case report.
Medicine (Baltimore)
December 2024
Department of Respiratory and Critical Care Medicine, The Second Hospital of Dalian Medical University, Dalian, Liaoning Province, China.
Article Synopsis
- Extramedullary plasmacytoma is a rare malignant tumor found in tissues outside of bone marrow, with primary pulmonary plasmacytoma (PPP) being particularly uncommon and diagnosed through biopsy.
- A 65-year-old woman experienced chronic cough and was hospitalized with acute chest pain, where imaging revealed extensive lung inflammation.
- The diagnosis was confirmed via bronchoscopy, leading to hormone anti-inflammatory treatment; however, the patient was lost to follow-up, emphasizing the need for awareness and biopsy in similar cases to ensure proper diagnosis and management of PPP.
Efficacy of Daratumumab-Based Regimens for Extramedullary Pulmonary Plasmacytoma: A Case Report.
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Hematology and Transplant Center, University Hospital "San Giovanni di Dio e Ruggi d'Aragona", Salerno, Italy.
Introduction: Multiple myeloma (MM) with pulmonary extramedullary disease is rare and usually associated with poor prognosis, and no data on daratumumab-based regimens have been reported yet.
Case Presentation: Here, a 64-year-old man with pulmonary plasmacytoma received daratumumab-based regimens and has achieved a very good partial response with lung mass disappearance and overall survival of 16 months. He did not receive autologous stem cell transplantation because of several comorbidities, such as severe drug-induced neuropathy and JAK2-mutated myeloproliferative neoplasm with marked splenomegaly.
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Background: We conduct a retrospective analysis of patients with pathological fractures resulting from upper extremity malignancies, focusing on the evaluation of treatment strategies employed.
Materials And Methods: We retrospectively studied 10 patients with metastatic bone tumors of the upper extremities. The study variables included tumor site, primary pathology, duration from the first diagnosis of the primary lesion to the occurrence of the pathological fracture, use of bone-modifying drugs, surgical technique, adjuvant therapy, postoperative functional assessment, Katagiri's score, American Society of Anesthesiologists physical status (ASA-PS), outcome, and correlations between the Eastern Cooperative Oncology Group Performance Status (ECOG-PS) and Musculoskeletal Tumor Society (MSTS) score.
Extraosseous Plasmacytomas: A Radiologist's Perspective-A Narrative Review of the Literature.
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August 2024
Department of Radiology, General University of Patras, 61000 Patras, Greece.
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- * EPs can appear in various body parts, including the lungs, breasts, and abdominal organs, making them tough to diagnose due to their similar imaging characteristics to other conditions.
- * The review highlights the importance of imaging for detecting EPs, but emphasizes that a histological confirmation is essential for an accurate diagnosis, especially for patients with a history of multiple myeloma, as timely diagnosis can greatly improve
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