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[Donepezil in patients with Alzheimer's disease--a critical appraisal of the AD2000 study].
Med Klin (Munich)
March 2005
Institut für Qualität undWirtschaftlichkeit im Gesundheitswesen, Köln.
The AD2000 study was a randomized placebo-controlled trial, the effects of donepezil, a cholinesterase inhibitor, in patients with Alzheimer's disease. It was the first long-term RCT not sponsored by the pharmaceutical industry. The study did not show any significant effect on patient-relevant outcomes.
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