Susac's syndrome or catastrophic antiphospholipid syndrome?

Lupus

Department of Autoimmune Diseases, Hospital Clinic, Barcelona, Catalonia, Spain.

Published: November 2004

Susac's syndrome is a microangiopathic disorder of unknown pathogenesis presenting with encephalopathy, hearing loss and branch retinal artery occlusions. The term 'catastrophic' antiphospholipid syndrome (APS) is used to define a subset of the APS characterized by thrombotic microangiopathy with clinical evidence of three or more organ involvement developed in a short period of time. We describe a patient with typical features of Susac's syndrome, that appeared in less than a week, in whom aPL were detected, thus fulfilling criteria for 'probable' catastrophic APS.

Download full-text PDF

Source
http://dx.doi.org/10.1191/0961203304lu1046crDOI Listing

Publication Analysis

Top Keywords

susac's syndrome
12
syndrome catastrophic
4
catastrophic antiphospholipid
4
antiphospholipid syndrome?
4
syndrome? susac's
4
syndrome microangiopathic
4
microangiopathic disorder
4
disorder unknown
4
unknown pathogenesis
4
pathogenesis presenting
4

Similar Publications

Spinal cord involvement in Susac Syndrome: a unique paediatric case.

Rheumatology (Oxford)

January 2025

Department of Pédiatrie Générale, Assistance Publique et Hôpitaux de Marseille (AP-HM), Marseille, France.

View Article and Find Full Text PDF

Susac is a rare systemic disease characterized by ischemic events involving the cochlea, brain, and retina. Delay in the diagnosis leads to sight-threatening complications such as neovascular glaucoma.

View Article and Find Full Text PDF

Susac's syndrome is a rare inflammatory microangiopathy characterized by the triad of retinopathy, encephalopathy, and hearing loss. The syndrome causes recurrent microinfarcts in these organs, which in turn manifests with repeated attacks of visual field loss, hearing loss and tinnitus, and various brain syndromes. These often lead to the significant accumulation of disability over time, particularly if there is a delay or failure in diagnosis.

View Article and Find Full Text PDF

Background And Objectives: Susac syndrome (SuS) is a rare disorder characterized by encephalopathy, branch retinal artery occlusion, and sensorineural hearing loss, often accompanied by vertigo. Recent updates to diagnostic criteria and treatment guidelines have been made. This study examines clinical manifestations; disease activity; and risk factors of disability, dependency, and return to work in patients with SuS.

View Article and Find Full Text PDF

Background: Susac syndrome (SuS) is a rare immune-mediated microangiopathy with potential disabling evolution. We aimed to analyze brain microstructural damage through diffusion tensor imaging (DTI) in SuS and determine its association with poor outcomes.

Method: CarESS study is a prospective multicenter national cohort study of patients with SuS.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!