Flooring materials evaluated consisted of three types of mesh (wire, steel, and plastic), three types of perforated floor (wood, styrofoam, and plastic), and three types of doweling (rigid, rotating, and padded). A solid wood floor with wood shavings litter served as a control. Parameters measured included body weight at 4, 6, and 8 wk and dressed carcass weight. Breast blisters, feather soilage, broken bones, feed consumption, percentage abdominal fat, and mortality rate for each floor type were also evaluated. Birds grown on wire mesh floors experienced a significant reduction in live body weight at 6 and 8 wk of age when compared with all other floor types tested. The remaining experimental floor types were comparable to the litter floor control group when using body weight as the performance criterion. The mesh floors experienced the highest incidence of breast blisters and the padded dowel group experienced the least. Feather soilage was a problem only with the perforated wood and styrofoam floor systems. Abdominal fat did not seem to be related to experimental floor type. The incidence of wing breakage during processing was significantly greater than leg breakage for all floor systems tested. Mortality was only a problem with the birds reared on wire mesh floors. The overall data suggests that a padded dowel floor system can be used to produce cage broilers about 2,500 g in weight without leg or breast damage and that these birds will be equivalent to those currently produced by the industry on a litter floor system.
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http://dx.doi.org/10.3382/ps.0710274 | DOI Listing |
Sci Rep
December 2024
Interventional Oncology, Johnson & Johnson Enterprise Innovation, Inc, 10th Floor 255 Main St, 02142, Cambridge, Boston, MA, USA.
The introduction of anti-PD-1/PD-L1 therapies revolutionized treatment for advanced non-small cell lung cancer (NSCLC), yet response rates remain modest, underscoring the need for predictive biomarkers. While a T cell inflamed gene expression profile (GEP) has predicted anti-PD-1 response in various cancers, it failed in a large NSCLC cohort from the Stand Up To Cancer-Mark (SU2C-MARK) Foundation. Re-analysis revealed that while the T cell inflamed GEP alone was not predictive, its performance improved significantly when combined with gene signatures of myeloid cell markers.
View Article and Find Full Text PDFJ Neurol
December 2024
Department of Neurosciences Rita Levi Montalcini, University of Turin, Turin, Italy.
Introduction: Non-motor symptoms (NMS) in Parkinson's disease (PD) can fluctuate daily, impacting patient quality of life. The Non-Motor Fluctuation Assessment (NoMoFA) Questionnaire, a recently validated tool, quantifies NMS fluctuations during ON- and OFF-medication states. Our study aimed to validate the Italian version of NoMoFA, comparing its results to the original validation and further exploring its clinimetric properties.
View Article and Find Full Text PDFSci Rep
December 2024
Dementia Research Centre, Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, University College London, 1st Floor, 8-11 Queen Square, London, WC1N 3AR, UK.
Previous research suggests that emotional prosody perception is impaired in neurodegenerative diseases like Alzheimer's disease (AD) and primary progressive aphasia (PPA). However, no previous research has investigated emotional prosody perception in these diseases under non-ideal listening conditions. We recruited 18 patients with AD, and 31 with PPA (nine logopenic (lvPPA); 11 nonfluent/agrammatic (nfvPPA) and 11 semantic (svPPA)), together with 24 healthy age-matched individuals.
View Article and Find Full Text PDFPediatr Rheumatol Online J
December 2024
Translational Genetics Research Group, La Fe Health Research Institute (IIS La Fe), Avenida Fernando Abril Martorell nº 106 Tower A, 7th Floor, Valencia, Spain.
Background: Aicardi-Goutières Syndrome is a monogenic type 1 interferonopathy with infantile onset, characterized by a variable degree of neurological damage. Approximately 7% of Aicardi-Goutières Syndrome cases are caused by pathogenic variants in the ADAR gene and are classified as Aicardi-Goutières Syndrome type 6. Here, we present a new homozygous pathogenic variant in the ADAR gene.
View Article and Find Full Text PDFOral Surg Oral Med Oral Pathol Oral Radiol
October 2024
Department of Biomedical Engineering, Ankara University, Ankara, Turkey.
Objective: The production of 3-dimensional models and materials according to preoperative virtual surgical planning is a time-consuming process and causes high costs. We aimed to demonstrate the navigation mediated reconstruction of the patients who underwent the removal of a tumoral mass in midfacial region according to their preoperatively prepared surgical plannings.
Study Design: Patients who underwent the removal of tumoral mass and reconstruction in their midfacial region were included in the study.
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