The synthesis and associated structure-activity relationships for gene transfection of a series of spermine-derived cationic gemini surfactants incorporating diamino acid headgroups and either identical (symmetrical) or different (unsymmetrical) lipophilic tailgroups is described. Transfection activity is found to depend critically upon the structural elements present.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1039/B410240A | DOI Listing |
Publication Analysis
Top Keywords
gemini surfactants
8
chain length
4
length transfection
4
transfection properties
4
properties spermine-based
4
spermine-based gemini
4
surfactants synthesis
4
synthesis associated
4
associated structure-activity
4
structure-activity relationships
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!