This study evaluated the costs of work-related stress in France. Three illnesses--cardiovascular diseases, depression, musculoskeletal diseases and back pain--that may result from exposure to stress are identified and the proportions of cases attributable to the risk factor are calculated from epidemiological studies. Two methodological hypotheses allow us to provide complementary evaluations of the social cost of occupational stress and raise the ethical questions inherent in the choice of methodology. For the year 2000 our model shows that of a working population of 23.53 million in France some 310,000-393,400 persons (1.3-1.7%) were affected by illnesses attributable to work-related stress, and that 2,300-3,600 persons died as a result of their illness. Work-related stress costs society between Euro 1,167 million and Euro 1,975 million in France, or 14.4-24.2% of the total spending of social security occupational illnesses and work injuries branch.
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http://dx.doi.org/10.1007/s10198-004-0251-4 | DOI Listing |
Free Radic Biol Med
January 2025
Wuxi School of Medicine, Jiangnan University, Wuxi, Jiangsu, 214122, China; Institute of Health and Medicine, Hefei Comprehensive National Science Center, Hefei 230601, China. Electronic address:
The emergence of cuproptosis, a novel form of regulated cell death, is induced by an excess of copper ions and has been associated with the progression of multiple diseases, including liver injury, cardiovascular disease, and neurodegenerative disorders. However, there are currently no inhibitors available for targeting specific cuproptosis-related pathways in therapy. Here, the compound merestinib (MTB) has been identified as a strong inhibitor of cuproptosis through screening of a kinase inhibitor library.
View Article and Find Full Text PDFSci Total Environ
January 2025
Department of Chemical Engineering, Tennessee Technological University, Cookeville, TN, United States. Electronic address:
The overall objective of the present work was to quantify how shear, coupled with varying salt concentration, affected the particle size distribution and relaxation/aggregation behavior for various organic sources of nonliving natural organic matter (NNOM) in surface water. NNOM has been implicated as a conditioning agent leading to the formation of biofilms such as algae. NNOM is also a responsible in surface waters for facilitated transport of a variety of anthropogenic pollutants.
View Article and Find Full Text PDFJ Psychiatr Res
January 2025
Department of Psychology, Reykjavik University Reykjavík, Reykjavík, Iceland. Electronic address:
The COVID-19 pandemic introduced numerous stressors and challenges that have had profound implications for mental health. This study examined the effects of the pandemic on mental health among Icelandic adults (n = 1766), using longitudinal survey data spanning three waves of data collection from 2019 to 2022. Symptoms of depression, anxiety, and stress increased from the beginning of the pandemic to the second time point, approximately one year into the pandemic, coinciding with reductions in happiness and social support.
View Article and Find Full Text PDFJ Clin Neurosci
January 2025
Family and Community Medicine Department, College of Medicine, King Khalid University, Abha, Saudi Arabia.
Background: Migraine is a common primary headache disorder that significantly affects academic life and is often associated with stress, depression, anxiety, and irregular sleep patterns among university students. This study aimed to assess the prevalence of migraine among King Khalid University (KKU) students, identify its determinants, and evaluate the impact of migraine and other headaches on academic life and performance.
Methods: An analytical cross-sectional study was conducted among 732 students from Colleges of Medicine, Pharmacy, Engineering, and Computer science.
Ecotoxicol Environ Saf
January 2025
Institute of Chemistry, Slovak Academy of Sciences, Dúbravská cesta 9, Bratislava 845 38, Slovakia. Electronic address:
We tested the effects of galactoglucomannan oligosaccharides (GGMOs) and/or cadmium (Cd) on peroxidase activity and the proteome in maize (Zea mays L.) roots and leaves. Our previous work confirmed that GGMOs ameliorate the symptoms of Cd stress in seedlings.
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