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Phenotype and Treatment Options for Mesenteric Lymph Node Cavitating Syndrome in Coeliac Disease: A Case Series and Literature Review.
J Clin Med
September 2024
Academic Unit of Gastroenterology, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield S10 2JF, UK.
Article Synopsis
- There is limited data on mesenteric lymph node cavitation syndrome (MLNCS), a rare and serious condition linked to coeliac disease, which can lead to central necrosis in enlarged lymph nodes; the largest related study dates back to 1984 and noted a poor prognosis.
- A recent study from 2000 to 2023 included 51 patients, revealing that common symptoms were weight loss (80%) and diarrhea (65%), with a significant number having persistent villous atrophy (88%) and hyposplenism (80%).
- The prognosis for MLNCS is poor, with a 43% overall mortality rate mainly due to complications like cachexia and infections; current treatment methods appear inadequate, suggesting a
Glucose-Stimulated Mucus Secretion by Goblet Cells Mitigates Intestinal Barrier Dysfunction in a Rat Model of Mesenteric Ischemia/Reperfusion Injury.
Curr Dev Nutr
September 2024
Department of Food Science and Biotechnology, National Chung Hsing University, Taichung, Taiwan.
Background: Superior mesenteric ischemia/reperfusion (I/R) causes barrier dysfunction and facilitates bacterial translocation (BT) in the small intestine, which can even lead to systemic sepsis. Our previous research showed that luminal administration of glucose and its anaerobic glycolytic metabolites exerted cytoprotective effects on epithelial cells and ameliorated I/R-induced BT in the liver and spleen. Notably, the reduction of BT occurs over the whole intestinal tract, not only restricted in the ligated glucose-containing loop.
View Article and Find Full Text PDFUltrasonographic features of intestinal lipogranulomatous lymphangitis in 10 dogs.
Vet Radiol Ultrasound
September 2023
Department of Diagnostic Imaging, Anicura Ospedale Veterinario "I Portoni Rossi", Zola Predosa, Bologna, Italy.
Intestinal lipogranulomatous lymphangitis (ILL) is a granulomatous inflammation of the lymphatic vessels of the intestinal wall and mesentery characterized by lipogranulomas. The purpose of this retrospective, multi-center, case series study is to report the ultrasonographic features of canine ILL. Ten dogs with a histologically confirmed ILL undergoing preoperative abdominal ultrasound were retrospectively included.
View Article and Find Full Text PDFAccumulative Effects of Multifrequency Microwave Exposure with 1.5 GHz and 2.8 GHz on the Structures and Functions of the Immune System.
Int J Environ Res Public Health
March 2023
Beijing Institute of Radiation Medicine, Beijing 100850, China.
Microwave ablation can produce immune activation due to thermal effects. However, the nonthermal effects of microwaves on the immune system are still largely unexplored. In this study, we sequentially exposed rats to 1.
View Article and Find Full Text PDFDelayed Diagnosis of Intestinal Tuberculosis: A Case Report.
Cureus
October 2022
Internal Medicine Department, Unidade Local de Saúde do Litoral Alentejano, Santiago do Cacém, PRT.
Abdominal tuberculosis is an uncommon clinical entity, and it can involve the gastrointestinal tract but also the peritoneum, lymph nodes, and solid organs. Its prevalence is higher among individuals from endemic regions for tuberculosis. Epidemiological risk factors associated with typical symptoms and complementary exams should prompt early treatment.
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