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Structural basis of Acinetobacter type IV pili targeting by an RNA virus.
Nat Commun
March 2024
Center for Phage Technology, Department of Biochemistry and Biophysics, Texas A&M University, College Station, TX, 77843, USA.
Acinetobacters pose a significant threat to human health, especially those with weakened immune systems. Type IV pili of acinetobacters play crucial roles in virulence and antibiotic resistance. Single-stranded RNA bacteriophages target the bacterial retractile pili, including type IV.
View Article and Find Full Text PDFA case of squamous cell carcinoma occurring on a scar of Buruli ulcer in Bouake, Ivory Coast.
Pan Afr Med J
November 2019
Department of Dermatology, University Hospital of Bouake, Bouake, Cote d'Ivoire.
Buruli ulcer is infectious necrotizing panniculitis due to . Buruli ulcer is healed by leaving dystrophic, fibrous and retractile scars. On these scars can occur long-term squamous cell carcinoma.
View Article and Find Full Text PDFPreputial reconstruction in hypospadias repair.
J Pediatr Urol
February 2017
Department of Paediatrics, Federico II University of Naples, Naples, Italy.
Objective: In principle, the prepuce can be reconstructed during hypospadias repair, but the procedure has not gained wide acceptance and preputial reconstruction (PR) is surrounded by several controversies.
Material And Methods: A review is provided of the technique for PR, how PR combines with the other steps of hypospadias repair, the risks of complications related to the urethroplasty and specific to PR, and the results of PR with particular regard to the relevance for the patient and his family.
Results: PR can be important for patients requiring hypospadias repair and their parents.
The cephalopod arm crown: appendage formation and differentiation in the Hawaiian bobtail squid .
Front Zool
September 2016
Department of Biology, University of Hawaii at Manoa, 2538 McCarthy Mall, Edmondson Hall 413, Honolulu, HI 96822 USA.
Background: Cephalopods are a highly derived class of molluscs that adapted their body plan to a more active and predatory lifestyle. One intriguing adaptation is the modification of the ventral foot to form a bilaterally symmetric arm crown, which constitutes a true morphological novelty in evolution. In addition, this structure shows many diversifications within the class of cephalopods and therefore offers an interesting opportunity to study the molecular underpinnings of the emergence of phenotypic novelties and their diversification.
View Article and Find Full Text PDFStructure of the Neisseria meningitidis outer membrane PilQ secretin complex at 12 A resolution.
J Biol Chem
September 2004
Department of Biomolecular Sciences, University of Manchester Institute of Science and Technology, Manchester M60 1QD, United Kingdom.
The bacterial pathogen Neisseria meningitidis expresses long, thin, retractile fibers (called type IV pili) from its cell surface and uses these adhesive structures to mediate primary attachment to epithelial cells during host colonization and invasion. PilQ is an outer membrane protein complex that is essential for the translocation of these pili across the outer membrane. Here, we present the structure of the PilQ complex determined by cryoelectron microscopy to 12 A resolution.
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