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Background: Streptococcal Toxic Shock Syndrome (STSS) is a life-threatening condition caused by bacterial toxins. The STSS triad encompasses high fever, hypotensive shock, and a "sunburn-like" rash with desquamation. STSS, like Toxic Shock Syndrome (TSS), is a rare complication of streptococcal infec-tions caused by Group A Streptococcus (GAS), Streptococcal pyogenes (S.

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Systemic capillary leak syndrome (SCLS) is a rare and life-threatening disorder characterized by acute hypotension, hypoalbuminemia, and hemoconcentration, which often results in severe respiratory complications, such as pulmonary edema. SCLS can be triggered by infections, including COVID-19, and is associated with a high mortality rate. Here, we report a case of COVID-19-associated SCLS in a 68-year-old man.

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Intussusception is a leading cause of acute intestinal obstruction in infants, typically presenting with a classic triad of intermittent abdominal pain, vomiting, and currant jelly stools. However, atypical presentations can lead to diagnostic delays, increasing the risk of complications. This report describes a seven-month-old male with an unusual presentation of lethargy and irritability, without overt gastrointestinal symptoms.

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Leiomyomas are benign tumors of the female genital tract, usually arising from the uterus. Vaginal leiomyomas are extremely rare. We describe here a case of vaginal leiomyoma in a 28-year-old unmarried woman who presented with excessive vaginal bleeding and acute retention of urine.

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Immune checkpoint inhibitors (ICIs), such as pembrolizumab, have revolutionized cancer therapy but can lead to severe immune-related adverse events (irAEs). We present a case of fulminant type 1 diabetes mellitus (T1DM) with diabetic ketoacidosis (DKA) and mesenteric ischemia in a 78-year-old woman with recurrent stage IIIC1 cervical cancer treated with pembrolizumab. Thirty-four days after initiating a pembrolizumab-containing regimen, she presented with vomiting, severe hyperglycemia, metabolic acidosis, and strongly positive urine ketones.

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