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Infect Disord Drug Targets
January 2025
HCA Healthcare Las Palmas/Del Sol Internal Medicine Program.
Background: Streptococcal Toxic Shock Syndrome (STSS) is a life-threatening condition caused by bacterial toxins. The STSS triad encompasses high fever, hypotensive shock, and a "sunburn-like" rash with desquamation. STSS, like Toxic Shock Syndrome (TSS), is a rare complication of streptococcal infec-tions caused by Group A Streptococcus (GAS), Streptococcal pyogenes (S.
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December 2024
Department of Critical Care Medicine, St. Luke's International Hospital, Tokyo, JPN.
Systemic capillary leak syndrome (SCLS) is a rare and life-threatening disorder characterized by acute hypotension, hypoalbuminemia, and hemoconcentration, which often results in severe respiratory complications, such as pulmonary edema. SCLS can be triggered by infections, including COVID-19, and is associated with a high mortality rate. Here, we report a case of COVID-19-associated SCLS in a 68-year-old man.
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December 2024
Radiology, The Second Health Cluster, Jeddah, SAU.
Intussusception is a leading cause of acute intestinal obstruction in infants, typically presenting with a classic triad of intermittent abdominal pain, vomiting, and currant jelly stools. However, atypical presentations can lead to diagnostic delays, increasing the risk of complications. This report describes a seven-month-old male with an unusual presentation of lethargy and irritability, without overt gastrointestinal symptoms.
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December 2024
Obstetrics and Gynaecology, Tata Main Hospital, Jamshedpur, IND.
Leiomyomas are benign tumors of the female genital tract, usually arising from the uterus. Vaginal leiomyomas are extremely rare. We describe here a case of vaginal leiomyoma in a 28-year-old unmarried woman who presented with excessive vaginal bleeding and acute retention of urine.
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December 2024
Department of Obstetrics and Gynecology, Osaka Metropolitan University Graduate School of Medicine, Osaka, JPN.
Immune checkpoint inhibitors (ICIs), such as pembrolizumab, have revolutionized cancer therapy but can lead to severe immune-related adverse events (irAEs). We present a case of fulminant type 1 diabetes mellitus (T1DM) with diabetic ketoacidosis (DKA) and mesenteric ischemia in a 78-year-old woman with recurrent stage IIIC1 cervical cancer treated with pembrolizumab. Thirty-four days after initiating a pembrolizumab-containing regimen, she presented with vomiting, severe hyperglycemia, metabolic acidosis, and strongly positive urine ketones.
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