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Work context and drinking behavior in the French public service: a qualitative study.
Front Public Health
November 2024
Laboratory "Health, Systemic, Process" (P2S), UR4129, University Claude Bernard Lyon 1, University of Lyon, Lyon, France.
Introduction: Alcohol use disorders (AUD) are a major public health problem. Among the working population, alcohol is the most frequently used psychoactive substance, as well as the most inappropriately used. Alcohol consumption reduces the worker's psychophysical integrity, leads to an increase in inappropriate behavior, accidents and injuries, and affects the safety and health of other workers.
View Article and Find Full Text PDFHepatoprotective effects of diosmin: a narrative review.
Naunyn Schmiedebergs Arch Pharmacol
August 2024
Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, Al-Azhar University, Assiut, 71524, Egypt.
Liver diseases represent a formidable global health threat. Hesperidin, a flavonoid found in citrus fruits, is the source of diosmin (DS). The in vivo and in vitro investigations of the pharmacological effects of DS reveal that it exhibits tremendous beneficial effects, such as fighting against inflammation, oxidative stress, and fibrosis.
View Article and Find Full Text PDFPrevalence, pattern and determinants of substance abuse among youths in a rural community of Osun State, Southwest Nigeria.
Afr Health Sci
December 2023
Department of Community Medicine, College of Health Sciences, Bowen University, Iwo Nigeria.
Study Objectives: This study assessed the prevalence, patterns and factors associated with substance abuse among youths of Ejigbo community, Osun State, Nigeria.
Method: This was a descriptive cross-sectional study which employed cluster sampling method to select 420 consenting youths (aged 15-24years). Data were collected using interviewer-administered, semi structured questionnaire.
Hepatocellular carcinoma and lipid metabolism: Novel targets and therapeutic strategies.
Cancer Lett
August 2024
Institute for Biotechnology, St. John's University, New York, NY, 11439, USA; College of Pharmacy and Health Sciences, St. John's University, New York, NY, 11439, USA. Electronic address:
Hepatocellular carcinoma (HCC) is an increasingly prevalent disease that is associated with high and continually rising mortality rates. Lipid metabolism holds a crucial role in the pathogenesis of HCC, in which abnormalities pertaining to the delicate balance of lipid synthesis, breakdown, and storage, predispose for the pathogenesis of the nonalcoholic fatty liver disease (NAFLD), a disease precursor to HCC. If caught early enough, HCC treatment may be curative.
View Article and Find Full Text PDFGenetic risk for trait aggression and alcohol use predict unique facets of alcohol-related aggression.
Psychol Addict Behav
June 2024
Department of Psychological Sciences, University of Missouri.
Article Synopsis
- The study investigates the genetic links between aggression and alcohol use, specifically focusing on how these genetic factors may influence alcohol-related aggression differently.
- Using polygenic risk scores (PRS) based on genome-wide data, the researchers analyzed the relationship between genetic risks and instances of alcohol-related aggression in two different groups: UCSF Family Alcoholism Study and the National Longitudinal Study of Adolescent to Adult Health.
- Results showed significant links between genetic risks for alcohol use disorder and aggression in the UCSF sample, but not in the Add Health sample, suggesting varying effects based on the context and type of aggression related to alcohol use.
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