Alteration of human conjunctival epithelial proliferation.

Arch Ophthalmol

Francis I. Proctor Foundation, University of California, San Francisco 94143-0730.

Published: March 1992

AI Article Synopsis

  • The study used a lab technique called bromodeoxyuridine to look at how often conjunctival cells are being labeled, indicating their DNA synthesis.
  • Patients with specific eye diseases, including superior limbic keratoconjunctivitis and squamous cell carcinoma of the conjunctiva, showed higher levels of DNA synthesis in their conjunctival cells.
  • Other conditions like drug-induced pseudopemphigoid and Stevens-Johnson syndrome also displayed increased conjunctival DNA synthesis.

Article Abstract

We used in vitro bromodeoxyuridine to analyze the labeling indexes of conjunctival cells in several external eye diseases. Patients with superior limbic keratoconjunctivitis, squamous cell carcinoma of the conjunctiva, drug-induced pseudopemphigoid, and Stevens-Johnson syndrome had increased conjunctival DNA synthesis.

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Source
http://dx.doi.org/10.1001/archopht.1992.01080150055027DOI Listing

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