Disuse atrophy of the quadriceps muscle and knee joint stiffness at the end of a 3-month period of immobilisation in patients with a fracture of the shaft of the femur is a common problem. A new approach to it was recently researched by applying a quadriceps endurance programme to a sample of this target population. Endurance capacity of matched experimental and control groups, consisting of 11 patients each, was tested at the end of the immobilisation period. Only the experimental group received the treatment intervention. Quadriceps endurance capacity in the experimental group at the end of the test period was at a 97% level compared with normal, uninjured subjects, while the control group's performance level was 57%. The difference is highly significant (P less than 0.0001). The problem of disuse atrophy had been successfully overcome in the experimental group. The unaffected leg of 10 patients from the same target population was also tested at the end of the immobilisation period. The mean value achieved was similar to the norm, i.e. there was no significant difference when compared with normal quadriceps endurance capacity.
Download full-text PDF |
Source |
---|
J Med Internet Res
January 2025
Department of Rehabilitation Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Background: Sarcopenia is closely associated with a poor quality of life and mortality, and its prevention and treatment represent a critical area of research. Resistance training is an effective treatment for older adults with sarcopenia. However, they often face challenges when receiving traditional rehabilitation treatments at hospitals.
View Article and Find Full Text PDFBMC Nephrol
January 2025
Department of Nephrology, Department of Clinical Sciences Lund, Nephrology, Faculty of Medicine, Skåne University Hospital and Lund University, Lund, Sweden.
Background: Physical performance is low and physical activity declines in people with chronic kidney disease (CKD). Both factors are associated with decreased survival. Our hypothesis was that improved physical performance after 12 months of exercise training would result in better survival in patients with CKD stages 3 to 5 not on kidney replacement therapy (KRT).
View Article and Find Full Text PDFPflugers Arch
January 2025
School of Physical Education and Sport of Ribeirão Preto, University of São Paulo (USP), Avenida Bandeirantes, 3900, Monte Alegre, Ribeirão Preto, São Paulo, 14040-907, Brazil.
The Notch signaling pathway is crucial for skeletal muscle development, regeneration, inflammation, and aging. This study investigated the association between interleukin-10 (IL-10) and the Notch pathway in C2C12 cells, as well as explored the effects of combined endurance and resistance exercise on the Notch and autophagy pathways in the skeletal muscle of senescence-accelerated mouse-resistant 1 Sedentary (SAMR1 CT), SAMR1 exercised (SAMR1 EX), senescence-accelerated prone mouse 8 Sedentary (SAMP8 CT), and SAMP8 exercised (SAMP8 EX). C2C12 myoblasts were transfected with siIL-10.
View Article and Find Full Text PDFPhytomedicine
January 2025
Department of Orthopedic Surgery, Hubei Provincial Hospital of Traditional Chinese Medicine, Hubei Shizhen Laboratory, Affiliated Hospital of Hubei University of Chinese Medicine, Wuhan 430061, China. Electronic address:
Background: Sarcopenia is currently a life-threatening disease for the elderly. Polygonatum sibiricum polysaccharide (PSP) has anti-oxidative stress and anti-inflammatory effects. However, the effects of PSP on skeletal muscle aging, myoblast differentiation and mitochondrial dysfunction through PI3K/Akt/mTOR signaling pathway has not been explored.
View Article and Find Full Text PDFJ Bodyw Mov Ther
March 2025
Postgraduate Program in Physical Exercise in Health Promotion, Northern University of Paraná (UNOPAR), Londrina, Paraná, Brazil; Postgraduate Program in Rehabilitation Sciences, University of Northern Paraná (UNOPAR), Londrina, Paraná, Brazil; Postgraduate Program in Human Movement Sciences, State University of Northern Paraná (UENP), Jacarezinho, Paraná, Brazil. Electronic address:
Background: Photobiomodulation therapy (PBMT) has recently been indicated as a potential therapeutic strategy in diverse health and sports contexts. However, its efficacy on muscle performance in female futsal players remains unknown. The purpose of this study was to investigate the dose-response effect of PBMT on muscle performance in female futsal players.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!