Similar Publications
Spatial transcriptomics of the epipharynx in long COVID identifies SARS-CoV-2 signalling pathways and the therapeutic potential of epipharyngeal abrasive therapy.
Sci Rep
March 2025
Section of Otolaryngology, Department of Medicine, Fukuoka Dental College, Fukuoka, 814-0193, Japan.
In this study, the critical role of the epipharynx in managing long-term coronavirus disease 2019 (COVID-19), and in particular, how residual SARS-CoV-2 RNA affects signalling pathways in the epipharynx were investigated via spatial gene expression analysis (Visium HD). Moreover, we hypothesize that epipharyngeal abrasive therapy (EAT) targeting the epipharynx could improve long COVID symptoms by modulating local inflammation and gene expression. We conducted a comparative analysis of the gene expression profiles of three patients with long COVID and two control individuals without COVID-19.
View Article and Find Full Text PDFA Systematic Review of Treatment Protocols in Auricular Pseudocysts.
Indian J Otolaryngol Head Neck Surg
January 2025
Department of ENT, Government Medical College, Gandhinagar, Kottayam, India.
A systematic review of literature on treatment modalities available with respect to efficacy, complications and recurrences so as to guide the clinician to better treat this enigmatic condition. A systematic search of PubMed, Google Scholar, Ovid and Cochrane databases. Articles in English that described or compared treatment were included.
View Article and Find Full Text PDFA Rare Case of Non-Invasive Fungal Sinusitis Caused by Scedosporium Apiospermum in an Immunocompetent Patient.
Indian J Otolaryngol Head Neck Surg
January 2025
Department of ENT, Jaipur National University Institute for Medical Sciences and Research Centre, Jaipur, India.
Unlabelled: Fungal sinusitis are very often caused by Aspergillus spp. Dematiaceae spp. and mucomycoses.
View Article and Find Full Text PDFAcid Assault: Unmasking the Toll of Laryngopharyngeal Reflux Disease on Vocal Health - A Literature Review.
Indian J Otolaryngol Head Neck Surg
February 2025
Department of ENT, Mahatma Gandhi Medical College and Research Institute, Sri Balaji Vidyapeeth University, Pillaiyarkuppam, Pondicherry, 607402 India.
Laryngopharyngeal reflux disease (LPRD) is characterized by the backflow of gastric contents into the laryngopharynx, distinct from gastroesophageal reflux disease (GERD). Prevalence among otolaryngology patients ranges from 4 to 30% and being the major cause for hoarseness of voice. Common symptoms include hoarseness, chronic coughing, globus sensation, throat clearing and endoscopic evaluation reveals signs like posterior commissure hypertrophy and vocal fold edema.
View Article and Find Full Text PDFThe Rapid Progression of Myelopathy Due to Cervical Epidural Fluid Collection From Metastatic Tumor in the Cervical Lamina: A Case Report.
Cureus
February 2025
Department of Spine Surgery, Kameda Medical Center, Chiba, JPN.
Various conditions can cause myelopathy due to cervical epidural fluid collection, including idiopathic cervical epidural hematoma, traumatic cervical epidural hematoma, infectious myelitis, epidural abscess, spinal cord infarction, post-traumatic cerebrospinal fluid (CSF) leakage, and epidural tumors. While physical compression from hematoma, abscess, or epidural tumors is common, and carcinomatous meningitis can cause CSF flow obstruction and accumulation leading to myelopathy, rapid progression of serous fluid collection causing myelopathy is rare. We report a case of myelopathy caused by rapid accumulation of epidural exudate from a metastatic tumor in the cervical lamina.
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