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Understanding the molecular profiling of diffuse gliomas classification: A brief overview.
Surg Neurol Int
June 2023
Research Institute, Fundación Universitaria de Ciencias de la Salud, Bogotá, Colombia.
Background: Gliomas represent almost 30% of all primary brain tumors and account for 80% of malignant primary ones. In the last two decades, significant progress has been made in understanding gliomas' molecular origin and development. These advancements have demonstrated a remarkable improvement in classification systems based on mutational markers, which contribute paramount information in addition to traditional histology-based classification.
View Article and Find Full Text PDFMonolithic Papain-Immobilized Enzyme Reactors for Automated Structural Characterization of Monoclonal Antibodies.
Front Mol Biosci
November 2021
Department of Drug Sciences, University of Pavia, Pavia, Italy.
The characterization of monoclonal antibodies (mAbs) requires laborious and time-consuming sample preparation steps before the liquid chromatography-mass spectrometry (LC-MS) analysis. Middle-up approaches entailing the use of specific proteases (papain, IdeS, etc.) emerged as practical and informative methods for mAb characterization.
View Article and Find Full Text PDFCorrection to: Team dynamics in emergency surgery teams: results from a first international survey.
World J Emerg Surg
November 2021
Department of Clinical, Diagnostic and Pediatric Sciences, University of Pavia, Polo Didattico "Cesare Brusotti" Viale Brambilla, 74, 27100, Pavia, Italy.
Team dynamics in emergency surgery teams: results from a first international survey.
World J Emerg Surg
September 2021
Department of Clinical, Diagnostic and Pediatric Sciences, University of Pavia, Polo Didattico "Cesare Brusotti" Viale Brambilla, 74, 27100, Pavia, Italy.
Background: Emergency surgery represents a unique context. Trauma teams are often multidisciplinary and need to operate under extreme stress and time constraints, sometimes with no awareness of the trauma's causes or the patient's personal and clinical information. In this perspective, the dynamics of how trauma teams function is fundamental to ensuring the best performance and outcomes.
View Article and Find Full Text PDFRating the incidence of iatrogenic vascular injuries in thoracic and lumbar spine surgery as regards the approach: A PRISMA-based literature review.
Eur Spine J
November 2021
Department of Clinical-Surgical, Diagnostic and Pediatric Sciences, Neurosurgery Unit, University of Pavia, Polo Didattico "Cesare Brusotti", Viale Brambilla, 74, 27100, Pavia, Italy.
Purpose: To assess the rate, timing of diagnosis, and repairing strategies of vascular injuries in thoracic and lumbar spine surgery as their relationship to the approach.
Methods: PubMed, Medline, and Embase databases were utilized for a comprehensive literature search based on keywords and mesh terms to find articles reporting iatrogenic vascular injury during thoracic and lumbar spine surgery. English articles published in the last ten years were selected.
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