The structural characterization of two new abietanes and a new spiro-fused tricyclic diterpene isolated from the roots of Hyptis martiusii is described. The first member of a new class of rearranged abietane diterpenoids designated martiusane was characterized by the use of 1D NMR and several 2D shift correlated NMR pulse sequences (1H,1H-COSY, HMQC, HMBC and NOESY). Unambiguous 1H and 13C chemical shift assignments for all compounds are reported.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1002/mrc.1489 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Anti-inflammatory and antinociceptive effect of BENTH leaves essential oil.
Biotechnol Rep (Amst)
September 2022
Laboratory of Pharmacology and Molecular Chemistry; Department of Biological Chemistry, Regional University of Cariri, Rua Coronel Antônio Luis 1161, Pimenta, CEP 63105-000, Crato, Ceará, Brazil.
Benth. also known as "cidreira brava", has some activities verified in the literature, such as antiulcerogenic, antimicrobial and antiedematogenic. This study aimed to verify the anti-inflammatory and antinociceptive effect of the leaves essential oil.
View Article and Find Full Text PDFEffects of the Hyptis martiusii Benth. leaf essential oil and 1,8-cineole (eucalyptol) on the central nervous system of mice.
Food Chem Toxicol
November 2019
Laboratory of Pharmacology of Natural Products, Regional University of Cariri, 1161 Cel., Antonio Luis St, 63105-000, Crato, CE, Brazil. Electronic address:
The aim of this study was to characterize the central effects of the Hyptis martiusii leaf essential oil (OEHM) and 1,8-cineole (eucalyptol) using behavioral animal models. Gas chromatography coupled to mass spectrometry (GC/MS) was used to characterize the chemical compounds present in the OEHM. For the behavioral tests, female Swiss mice treated with the OEHM (25, 50, 100 and 200 mg/kg, i.
View Article and Find Full Text PDFPhysico-chemical characterization and antibacterial activity of inclusion complexes of Hyptis martiusii Benth essential oil in β-cyclodextrin.
Biomed Pharmacother
May 2017
Department of Biological Chemistry, Regional University of Cariri, Crato, Ceará, Brazil. Electronic address:
Cyclodextrins (CDs) have been used as important pharmaceutical excipients for improve the physicochemical properties of the drugs of low solubility as the essential oil of Hyptis martiusii. This oil is important therapeutically, but the low solubility and bioavailability compromises your use. Therein, the aim of this study was to obtain and to characterize physico-chemically the samples obtained by physical mixture (PM), paste complexation (PC) and slurry complexation (SC) of the essential oil Hyptis martiusii (EOHM) in β-CD, and to compare the antibacterial and modulatory-antibiotic activity of products obtained and oil free.
View Article and Find Full Text PDFEvaluation of chemical composition and antiedematogenic activity of the essential oil of Benth.
Saudi J Biol Sci
February 2017
Department of Biological Chemistry, Laboratory of Pharmacology and Molecular Chemistry, Regional University of Cariri - URCA, Crato, CE, Brazil.
Evaluations of the therapeutic potential of medicinal plants and their components have been the subject of many studies. Furthermore, the biological activities of various plant species have been reported in various pieces of literature. Benth (Lamiaceae), popularly known as "mad balm" is commonly found in the North, Southeast, and Northeast of Brazil.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!