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40th Anniversary of the TIMI Study Group.

Circulation

January 2025

TIMI (Thrombolysis in Myocardial Infarction) Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital, and Department of Medicine, Harvard Medical School, Boston, MA.

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Introduction: Although robot-assisted surgery has been rapidly gaining popularity in recent years, few reports have examined the impact of individual robotic arm movements on surgical outcomes. This study investigated the relationship between extra arm (EA) usage and experience of surgeons in robot-assisted surgery.

Methods: A total of 176 robot-assisted rectal resections were performed by three surgeons from 2018 to 2022.

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Objective: The goal of this study was to assess the impact of fractional curve (FC) severity on curve progression and postoperative outcomes in patients undergoing adult idiopathic scoliosis (AdIS) correction.

Methods: Patients with AdIS who had preoperative coronal plane deformity and who had undergone thoracolumbar fusion with a lowermost instrumented vertebra (LIV) between L1 and L4 were included. Patients were stratified by 6-week postoperative FC severity (small FC, ≤ 40th percentile, large FC, ≥ 60th percentile of the entire cohort; calculated as the Cobb angle between LIV and S1) and age groups.

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Adhesive lipophilic gels delivering rapamycin prevent oral leukoplakia from malignant transformation.

Mater Today Bio

December 2024

State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Chinese Academy of Medical Sciences Research Unit of Oral Carcinogenesis and Management, Med-X Center for Materials, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, 610041, PR China.

Oral leukoplakia (OLK) is the most emblematic oral potentially malignant disorder that may precede the diagnosis of oral squamous cell carcinoma (OSCC) and has an overall malignant transformation rate of 9.8 %. Early intervention is crucial to reduce the malignant transformation rate from OLK to OSCC but the lack of effective local pharmaceutical preparations poses a challenge to clinical management.

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Article Synopsis
  • Meckel's diverticulum (MD) is the most common congenital gastrointestinal anomaly, found in about 2% of people, and is rarely symptomatic in adults.
  • This case highlights a 46-year-old male who experienced abdominal pain due to Meckel's diverticulitis, which had formed a fistula with the abdominal wall, and was also found to have a benign inflammatory myofibroblastic tumor (IMT) on imaging.
  • After surgery for the diverticulitis and complications like an anastomotic leak, the patient ultimately recovered, and this case emphasizes the importance of thorough diagnostic work to uncover incidental findings that can impact treatment.
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