Vascular involvement in neurofibromatosis sometimes occurs and usually affects larger blood vessels of internal organs. We describe an unusual case of a now 41-year-old man with extensive skin involvement with ulcerations and histopathologic features of fibromuscular dysplasia, which has not been previously reported in the skin.
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http://dx.doi.org/10.1016/j.jaad.2004.04.004 | DOI Listing |
Arch Dermatol Res
January 2025
Cellular and Molecular Research Center, Qom University of Medical Sciences, Qom, Iran.
Invading blood cells, extracellular tissue, and soluble mediators all play important roles in the wound-healing process. There is a substantial global burden of disease and mortality attributable to skin defects that do not heal. About 1% to 2% of the population in industrialized nations suffers from chronic wounds that don't heal, despite healthcare breakthroughs; this condition is very costly, costing about $25 billion each year in the US alone.
View Article and Find Full Text PDFJ Foot Ankle Res
March 2025
VA RR&D Center for Limb Loss and MoBility (CLiMB), VA Puget Sound Health Care System, Seattle, WA, USA.
Background: The patient-specific shape of custom accommodative insoles for individuals with diabetes provides full foot-to-insole contact, offloading areas with high plantar pressures and reducing ulceration risk. To design the insole surface, plantar surface shape is captured, traditionally with a foam crush box impression or more recently with 3D scans of the foot. Beyond discrete measurements of the foot, the overall plantar surface shapes obtained from these different methods have yet to be compared, however, differences in the shapes captured by these methods may affect the insole's surface geometry design and subsequent performance.
View Article and Find Full Text PDFJ Nanobiotechnology
January 2025
Shandong Key Laboratory of Proteins and Peptides Pharmaceutical Engineering, Shandong Universities Key Laboratory of Biological Medicine, School of Life Science and Technology, Shandong Second Medical University, 7166 # Baotong West Street, Weifang, Shandong, 261053, People's Republic of China.
Background: Diabetic foot ulcers (DFU) are severe complications of diabetes, posing significant health and societal challenges. Accumulation of reactive oxygen species (ROS) and elevated glucose levels are primary factors affecting diabetic wound healing. Achieving effective treatment by reducing ROS alone is challenging, as high glucose levels continuously drive ROS production.
View Article and Find Full Text PDFNurs Clin North Am
March 2025
Children's Surgery Center, UC Davis Health- ATTN, 4301 X Street, Sacramento, CA 95817, USA. Electronic address:
Pressure injury (PI) prevention in the operating room (OR) has unique considerations based on the patient, procedure, position for the surgical procedure, and available positioning devices. Patient-specific factors contribute to their risk of incurring an intraoperative PI from the American Society of Anesthesiologists classification, sex, body mass index, comorbidities, age, and nutritional status. Additionally, there are surgery-specific risk factors such as length of procedure, intraoperative hypotension, lack of normothermia, and intraoperative blood loss.
View Article and Find Full Text PDFNurs Clin North Am
March 2025
Lizzie Wounds, 107 Meadowcrest Lane, Douglassville, PA 19518, USA.
The circulatory and lymphatic systems play vital roles at the capillary level and throughout our bodies. Venous disease can lead to water-rich edema which this fluid is removed by an intact lymphatic system. However, if the lymphatic system is constantly tasked with removing edema, it can becomes damaged over time.
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