Relationship between phenotypic and genotypic florfenicol resistance in Escherichia coli.

Antimicrob Agents Chemother

Department of Veterinary and Biomedical Sciences, College of Veterinary Medicine, University of Minnesota, 300A VSB, 1971 Commonwealth Ave., St. Paul, MN 55108, USA.

Published: October 2004

This study evaluated the relationship between florfenicol resistance and flo genotypes in 1,987 Escherichia coli isolates from cattle. The flo gene was detected in 164 isolates, all of which expressed resistance to florfenicol at MICs of >/=256 microg/ml. The florfenicol MICs for all isolates that lacked flo were

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC521924PMC
http://dx.doi.org/10.1128/AAC.48.10.4047-4049.2004DOI Listing

Publication Analysis

Top Keywords

florfenicol resistance
8
escherichia coli
8
florfenicol mics
8
relationship phenotypic
4
phenotypic genotypic
4
florfenicol
4
genotypic florfenicol
4
resistance escherichia
4
coli study
4
study evaluated
4

Similar Publications

, commonly known as , is a critical zoonotic pathogen that significantly reduces milk yield and product quality and poses a significant risk to public health. Although is increasingly recognised as a principal agent causing milkborne infections, research dedicated to this pathogen in dairy cattle has been less extensive than that of other pathogens. This study aimed to examine the antibiotic resistance profiles of derived from dairy cows and assess its pathogenicity using validated in vivo models.

View Article and Find Full Text PDF

Research note: Prevalence and genetic characteristics of pathogenic E. coli isolates from domestic pigeons in central China.

Poult Sci

December 2024

Key Laboratory of Prevention and Control Agents for Animal Bacteriosis (Ministry of Agriculture and Rural Affairs), Hubei Provincial Key Laboratory of Animal Pathogenic Microbiology, Institute of Animal Husbandry and Veterinary, Hubei Academy of Agricultural Sciences, Wuhan 430064, China. Electronic address:

Pigeon has become popular as a food recently, due to their highly nutritive valuE. colibacillosis, which is caused by pathogenic E. coli, is one of the most important bacterial diseases in pigeon breeding.

View Article and Find Full Text PDF

Assessment of anti-MRSA activity of auranofin and florfenicol combination: a PK/PD analysis.

J Appl Microbiol

December 2024

State Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, South China Agricultural University, No. 483 Wushan Road, Guangzhou, 510642, China.

Aims: Methicillin-resistant Staphylococcus aureus (MRSA) is an important zoonotic pathogen with multidrug-resistant phenotypes increasingly prevalent in both human and veterinary clinics. This study evaluated the potential of auranofin (AF) as an antibiotic adjuvant to enhance the anti-MRSA activity of florfenicol (FFC) and established a pharmacokinetic/pharmacodynamic (PK/PD) model to compare the efficacy of FFC alone or in combination with AF against MRSA.

Methods And Results: We observed an increased susceptibility and significant synergistic effects of MRSA to FFC in the presence of AF.

View Article and Find Full Text PDF

The prevalence of antimicrobial resistance originating from animals presents a significant threat to the treatment of animal disease, public health, and food safety. Researchers have focused on antibiotic resistance in (), yet there are few reports on the resistance change during the feeding cycle. The purpose of this study was to investigate the prevalence and antibiotic resistance changes of in animal, environmental, and human samples during the broiler feeding cycle.

View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to establish epidemiological cut-off values for the minimum inhibitory concentrations (MICs) of 10 antimicrobial agents against the bacteria Vibrio parahaemolyticus using standardized testing methods.
  • Eight laboratories conducted broth microdilution tests at two different temperatures (35°C and 28°C) to assess the effect of incubation temperature on MIC values, finding that many values were consistent across both temperatures.
  • The generated data will be submitted to the Clinical and Laboratory Standards Institute to help set international standards for interpreting antimicrobial susceptibility tests for this species.
View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!