The contribution of long polar fimbriae to intestinal colonization by Escherichia coli O157:H7 was evaluated in sheep, conventional pigs, and gnotobiotic piglets. E. coli O157:H7 strains with lpfA1 and lpfA2 mutated were recovered in significantly lower numbers and caused fewer attachment and effacement lesions than the parent strain.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC517566PMC
http://dx.doi.org/10.1128/IAI.72.10.6168-6171.2004DOI Listing

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