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Evaluation of the Relationship Between Facial Measurements and Esthetic Evaluation of the Face in Patients With a Vertical Growth Pattern.
Cureus
January 2025
Department of Orthodontics, School of Dental Sciences, University Sains Malaysia, Kota Bharu, MYS.
Background: Soft tissue specifications and facial values vary depending on the underlying skeletal structures. To achieve the ideal treatment result and patient satisfaction, one must know the attractive soft tissue specifications compatible with each type of malocclusion. This study aims to analyze the facial measurements that contribute to perceived facial attractiveness in patients with vertical growth patterns and skeletal class I malocclusion, focusing on gender-specific differences.
View Article and Find Full Text PDFComparison of Band Percentage vs Immature Granulocyte Percentage in the Setting of Possible Infection Principle Investigators.
Adv Hematol
December 2024
Department of Pulmonary and Critical Care, Elkhart General Hospital, Elkhart, Indiana, USA.
Sepsis is a major cause of mortality worldwide. Early identification and treatment are critical to improve survival. Band count has been used as part of SIRS criteria for the early identification of potentially septic patients.
View Article and Find Full Text PDFKnowledge and Attitudes of Healthcare Professionals Regarding Disabilities in Eastern India.
Cureus
December 2024
General Surgery, All India Institute of Medical Sciences, Deoghar, Deoghar, IND.
Background: Globally, a substantial portion of the population lives with significant disabilities. Despite advancements, individuals with disabilities continue to experience poorer health outcomes, often due to inadequate knowledge and attitudes among healthcare providers. This study aimed to evaluate the knowledge and attitudes of healthcare professionals regarding disabilities in a tertiary care setting.
View Article and Find Full Text PDFGlobally, drug-resistant tuberculosis (DR-TB) is responsible for 13% of mortality attributable to antimicrobial resistance. In Ethiopia, extrapulmonary tuberculosis (EPTB) is a significant public health challenge, and drug resistance (DR) in EPTB is often overlooked. In a cross-sectional study conducted between August 2022 and October 2023, we aimed to explore the magnitude of phenotypic drug resistance and identify genetic mutations linked to resistance using 189 Mycobacterium tuberculosis (MTB) isolates cultured from extrapulmonary clinical specimens.
View Article and Find Full Text PDFAnti-gene oligonucleotide clamps invade dsDNA and downregulate expression.
Mol Ther Nucleic Acids
December 2024
Department of Laboratory Medicine, Karolinska Institutet, ANA Futura, Alfred Nobels Allé 8, 14152 Huddinge, Stockholm, Sweden.
Anti-gene oligonucleotides belong to a group of therapeutic compounds, which, in contrast to antisense oligonucleotides, bind to DNA. Clamp anti-gene oligonucleotides bind through a double-stranded invasion mechanism. With two arms connected by a linker, they hybridize to one of the DNA strands forming Watson-Crick and Hoogsteen hydrogen bonds.
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