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Dietary Patterns, Serum BDNF and Fatty Acid Profiles in Physically Active Male Young Adults: A Cluster Analysis Study.
Nutrients
December 2024
The Kielanowski Institute of Animal Physiology and Nutrition, Polish Academy of Sciences, 05-110 Jabłonna, Poland.
Although physical activity and balanced diet may increase peripheral brain-derived neurotrophic factor (BDNF) concentration, little is known about whether these factors modify BDNF content in physically active individuals and whether the serum fatty acid (FA) profile is related. This study aimed to evaluate quality of diet, identify specific dietary patterns and assess their influence on BDNF and FA levels in serum. It is hypothesized that there is a correlation between diet quality and the concentrations of BDNF and FA in the serum of physically active male individuals.
View Article and Find Full Text PDFLong-term results of revision total hip arthroplasties using cementless stems and allografts for paprosky type IIIB and IV femoral defects short title: Revision hip arthroplasty in type IIIB and IV femoral defects.
Int Orthop
January 2025
The Joint Replacement Center of Seoul Metropolitan Government SeoNam Hospital, Seoul, Republic of Korea.
Article Synopsis
- This study evaluated the long-term clinical outcomes of revision total hip arthroplasty (THA) in patients with severe femoral bone defects, using established scoring systems to measure results.
- Results showed significant improvements in hip function scores and high rates of bone ingrowth (91%) with cortical strut allografts well incorporated in most patients.
- The survival rate of the femoral components after an average follow-up of 26.5 years was 91%, indicating positive long-term outcomes for patients undergoing this procedure.
Optimal QT Correction Formula for Older Chinese: Guangzhou Biobank Cohort Study.
Cardiology
October 2024
School of Public Health, Sun Yat-Sen University, Guangzhou, China.
Introduction: To identify the optimal QT correction formula for generating corrected QT (QTc) and cutoffs for prolonged QTc, and examine the associations with mortality and cardiovascular disease (CVD) in older Chinese.
Methods: A prospective study included 24,611 Chinese aged 50+ years and without CVD at 2003-2008 from Guangzhou Biobank Cohort Study. QT interval was corrected by Bazett, Fridericia, Framingham and Hodges formulas.
Chinese utility weights for the EORTC cancer-specific utility instrument QLU-C10D.
Qual Life Res
December 2024
Saw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore.
Objective: The aim of this study is to provide Chinese utility weights for the European Organization for Research and Treatment of Cancer Quality of Life Utility Measure-Core 10 Dimensions (EORTC QLU-C10D) which is a preference-based cancer-specific utility instrument derived from the EORTC QLQ-C30.
Methods: We conducted an online survey of the general population in China, with quota sampling for age and gender. Each respondent was asked to complete a discrete choice experimental survey consisting of 16 randomly selected choice sets.
Triple-Negative Myelofibrosis: Disease Features, Response to Treatment and Outcomes.
Clin Lymphoma Myeloma Leuk
July 2024
Department of Malignant Hematology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL. Electronic address:
Article Synopsis
- - Myelofibrosis is a severe form of blood cancer, with the triple-negative subtype (TN-MF) being particularly aggressive and linked to the worst patient outcomes, accounting for only 5%-10% of cases.
- - In a study involving 626 patients, TN-MF was associated with significantly lower overall survival rates, increased leukemic transformation, and distinct clinical features such as more severe anemia and lower platelet counts compared to non-TN patients.
- - The research highlighted that patients with TN-MF had a lower response rate and shorter duration of response to the treatment ruxolitinib, indicating a need for further investigation into effective therapies for this difficult-to-treat subtype.
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