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Agricultural Wastes to Value-Added Products: Economic and Environmental Perspectives for Waste Conversion.
Adv Biochem Eng Biotechnol
December 2024
Plant Ecology and Environmental Botany Unit, Department of Plant Biology, University of Ilorin, Ilorin, Nigeria.
The conversion of agricultural wastes to value-added products has emerged as a pivotal strategy in fostering economic transformation. This chapter explores the transformative potential of converting agricultural residues into valued commodities that contribute to sustainability and economic growth. Agricultural wastes, often considered environmental liabilities, possess untapped benefits with great economic value.
View Article and Find Full Text PDFIntegrating In Silico and In Vitro Tools for Optimized Antibody Development-Design of Therapeutic Anti-oxMIF Antibodies.
Antibodies (Basel)
December 2024
OncoOne Research & Development GmbH, Karl-Farkas-Gasse 22, A-1030 Vienna, Austria.
Background: Rigorous assessment of antibody developability is crucial for optimizing lead candidates before progressing to clinical studies. Recent advances in predictive tools for protein structures, surface properties, stability, and immunogenicity have streamlined the development of new biologics. However, accurate prediction of the impact of single amino acid substitutions on antibody structures remains challenging, due to the diversity of complementarity-determining regions (CDRs), particularly CDR3s.
View Article and Find Full Text PDFPlants used for the management of venereal diseases in sub-Saharan Africa: a systematic review and critical assessment of their research status.
Trop Med Health
December 2024
School of Life Sciences, College of Agriculture, Engineering and Science, University of KwaZulu-Natal, Westville, 4001, South Africa.
Background: Sub-Saharan Africa faces one of the highest burdens of venereal diseases (VDs) globally. This review aims to critically evaluate the existing literature on the diverse Indigenous knowledge and medicinal plants utilised for treating VDs in sub-Saharan Africa.
Methods: We used the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) protocol to guide the execution of the review.
Characterizing the therapeutical use of ketamine for adolescent rats of both sexes: Antidepressant-like efficacy and safety profile.
Biomed Pharmacother
December 2024
IUNICS, University of the Balearic Islands, Palma, Spain; Health Research Institute of the Balearic Islands (IdISBa), Palma, Spain; Department of Medicine, University of the Balearic Islands, Palma, Spain. Electronic address:
While ketamine was approved for treatment-resistant depression in adult patients, its efficacy and safety profile for adolescence still requires further characterization. In this context, prior preclinical studies have shown that sub-anesthetic doses of ketamine during adolescence exert antidepressant-like effects in rodents in a dose- and sex-dependent manner. However, additional studies evaluating the short- and long-term safety profile of ketamine at the doses necessary to induce antidepressant-like effects are needed.
View Article and Find Full Text PDFEvaluating the Impact of Artificial Intelligence (AI) on Clinical Documentation Efficiency and Accuracy Across Clinical Settings: A Scoping Review.
Cureus
November 2024
General Internal Medicine, University Hospitals Plymouth NHS Trust, Plymouth, GBR.
Artificial intelligence (AI) technologies (natural language processing (NLP), speech recognition (SR), and machine learning (ML)) can transform clinical documentation in healthcare. This scoping review evaluates the impact of AI on the accuracy and efficiency of clinical documentation across various clinical settings (hospital wards, emergency departments, and outpatient clinics). We found 176 articles by applying a specific search string on Ovid.
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