In the present experiments, we examined whether shifts of attention selectively interfere with the maintenance of both verbal and spatial information in working memory and whether the interference produced by eye movements is due to the attention shifts that accompany them. In Experiment 1, subjects performed either a spatial or a verbal working memory task, along with a secondary task requiring fixation or a secondary task requiring shifts of attention. The results indicated that attention shifts interfered with spatial, but not with verbal, working memory, suggesting that the interference is specific to processes within the visuospatial sketchpad. In Experiment 2, subjects performed a primary spatial working memory task, along with a secondary task requiring fixation, an eye movement, or an attention shift executed in the absence of an eye movement. The results indicated that both eye movements and attention shifts interfered with spatial working memory. Eye movements interfered to a much greater extent than shifts of attention, however, suggesting that eye movements may contribute a unique source of interference, over and above the interference produced by the attention shifts that accompany them.
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Handb Clin Neurol
March 2025
Laboratory of Neuropsychology of Memory, IRCSS Santa Lucia Foundation, Rome, Italy; Department of Systems Medicine, Tor Vergata University, Rome, Italy. Electronic address:
The term "episodic memory" refers to our ability to remember past personal experiences. This ability is severely disrupted following bilateral damage to a dedicated neural substrate located symmetrically in the mesial temporal lobes. Milder deficits are also observed following unilateral damage to the same structures.
View Article and Find Full Text PDFHandb Clin Neurol
March 2025
Western Institute for Neuroscience, Western University, London, ON, Canada; Department of Computer Science, Western University, London, ON, Canada; Department of Statistical and Actuarial Sciences, Western University, London, ON, Canada.
The cerebellum is a subcortical structure tucked underneath the cerebrum that contains the majority of neurons in the brain, despite its small size. While it has received less attention in the study of brain asymmetries than the cerebrum, structural asymmetries in the cerebellum have been found in cerebellar volume that mirror cerebral asymmetries. Larger cerebellar structures have been reported on the right compared to the left, either for the whole cerebellar hemisphere or the anterior part of the cerebellum, with the latter accompanied by a left increase in the posterior cerebellum.
View Article and Find Full Text PDFSchizophr Res
March 2025
Department of Psychiatry, McLean Hospital, Harvard Medical School, Belmont, United States. Electronic address:
Background: P3a event-related potential (ERP) is considered a potential biomarker for schizophrenia (SZ), can be elicited through both passive two-stimulus and active three-stimulus auditory oddball paradigms. While both types of P3a reflect involuntary attention shifts, the nuanced understanding of what P3a represents in different contexts is important and rarely studied. This study aims to examine correlations between P3a ERPs elicited from different paradigms and associations of each P3a with cognitive function, clinical symptoms, and antipsychotic medication.
View Article and Find Full Text PDFJ Colloid Interface Sci
March 2025
School of Materials Science and Engineering, Harbin Institute of Technology, Harbin 150001, China; Heilongjiang Provincial Key Laboratory of Advanced Quantum Functional Materials and Sensor Devices, Harbin 150001, China. Electronic address:
Optical synaptic devices (OSDs) have neuromorphic vision sensing capability showing great potential in breaking the von Neumann bottleneck and facilitating future artificial vision systems. However, the applications of two-dimensional (2D) material-based OSDs are still impeded by complicated structures, preparation techniques and so on. In this work, we propose a 2D OSD based on BiSe films prepared by a chemical vapor deposition method followed by an in-situ thermal treatment.
View Article and Find Full Text PDFMult Scler Relat Disord
March 2025
Department of Physical Medicine & Rehabilitation, Rutgers - New Jersey Medical School, 183 South Orange Avenue, Suite F-1560, Newark, NJ 07101, USA; Center for Neuropsychology and Neuroscience Research, Kessler Foundation, 120 Eagle Rock Avenue, Suite 100, East Hanover, NJ 07936, USA. Electronic address:
Background: Cognitive impairment and fatigue are two prevalent symptoms of multiple sclerosis (MS). Fatigue is often thought to be associated with slower processing speed. The Symbol Digit Modalities Test (SDMT) is a widely used assessment of processing speed in MS, but it has also been shown to tap into working memory as well.
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