A rare case of invasive ductal carcinoma within a fibroadenoma of the breast in a 42-year-old woman is reported. The patient had a well-defined mass, measuring 6.0 x 5.0 cm, in the upper lateral quadrant of the left breast. Physical examination suggested fibroadenoma. Ultrasonography and mammography revealed some malignant findings. Needle biopsy demonstrated fibroadenoma. Frozen section revealed invasive ductal carcinoma, scirrhous type, arising in a fibroadenoma; muscle-preserving mastectomy was performed. Only 16 cases of carcinoma within a fibroadenoma of the breast have been reported in the literature in Japan. Carcinoma in a fibroadenoma should be treated on the basis of the therapeutic criteria for ordinary carcinoma.
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http://dx.doi.org/10.1007/s10147-004-0401-9 | DOI Listing |
Front Med (Lausanne)
December 2024
Department of Ultrasound, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Background: Contrast-enhanced ultrasound (CEUS) shows potential for the differential diagnosis of breast lesions in general, but its effectiveness remains unclear for the differential diagnosis of lesions highly suspicious for breast cancers.
Objective: This study aimed to evaluate the diagnostic value of CEUS in differentiating pathological subtypes of suspicious breast lesions defined as category 4 of US-BI-RADS.
Methods: The dataset of 150 breast lesions was prospectively collected from 150 patients who underwent routine ultrasound and CEUS examination and were highly suspected of having breast cancers.
Diagnostics (Basel)
December 2024
Department of Surgery, School of Medicine, Acıbadem Mehmet Ali Aydınlar University, 34752 Istanbul, Turkey.
Background: Somatostatin receptors (SSTRs) are expressed in most neuroendocrine neoplasms, particularly in gastroenteropancreatic neuroendocrine tumours, and have been utilised as diagnostic markers and therapeutic targets. The radioiodinated somatostatin analogue 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid- Tyr3-octreotate (DOTATATE) has been employed for SSTR targeting for either diagnostic or therapeutic purposes depending on the labelling with Gallium or Lutetium, respectively. SSTR expression is reported in a subset of breast adenocarcinoma and breast neuroendocrine carcinomas; however, minimal knowledge exists regarding their expression in fibroepithelial (biphasic) breast lesions such as fibroadenoma and phyllodes tumours.
View Article and Find Full Text PDFAcad Radiol
December 2024
Department of Radiology, Istanbul University-Cerrahpasa, Cerrahpasa Faculty of Medicine, Istanbul, Türkiye (Y.K., S.H.K., S.A.K., R.H., M.H.Y.).
Rationale And Objectives: The study aimed to evaluate demographic and radiological characteristics of breast incidentalomas found on 18-fluorodeoxyglucose Positron Emission Tomography-Computed Tomography (F-FDG PET-CT) performed for extramammary indications.
Materials And Methods: A total of 12633 F-FDG PET-CT scans performed between January 1, 2018 and January 1, 2024, were retrospectively reviewed. Breast incidentalomas that had undergone breast imaging, tissue diagnosis, or at least 2-year radiological follow-up were included.
Cureus
November 2024
Division of Surgical Pathology, Institute of Science Tokyo Hospital, Tokyo, JPN.
A 49-year-old woman visited our hospital after noticing an enlarged left breast mass. After a biopsy, she was diagnosed with fibroadenoma and underwent tumor resection. Postoperative pathology revealed squamous cell carcinoma (SCC) within a benign phyllodes tumor.
View Article and Find Full Text PDFCureus
November 2024
Department of Pathology, Father Muller Medical College, Mangalore, IND.
Axillary swellings, particularly in women, often raise suspicion due to the high association of such swellings with breast carcinoma manifesting as metastatic lymph node involvement. Tuberculous lymphadenopathy is one of the primary diagnoses in India. Fibroadenomas are common benign breast tumors, but their occurrence in the axilla, arising from ectopic breast tissue (EBT), is rare and may present a diagnostic challenge.
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