Mortality rates and antihypertensive therapy in extreme old age.

Arch Gerontol Geriatr

Cattedra di Geriatria, Istituto di I Clinica Medica-Università La Sapienza, Viale del Policlinico 155, 00161 Roma, Italy.

Published: March 2005

The impact of hypertension on survival in extremely old age has shown different features in different studies, with equal or lower mortality rates in hypertensive patients and lower reduction of risk in treated patients. In a population (n=414) of old community dwellers (mean age 88.4 years) the prevalence of hypertension was 52.2%. Hypertensive patients presented a lower mortality rate (14.2 per 100 person-years) as compared to the general population (15.4) and to non-hypertensives (16.6). Hypertensives were divided into four groups according to treatment. Best survival was shown by patients under treatment with antihypertensives alone (9.8) or in association with diuretics (9.9), and worst survival by patients under a diuretic-based treatment (25.1). These data were confirmed by multivariate analysis. The better survival of hypertensive very old people could be related to the use of a proper pharmacotherapy.

Download full-text PDF

Source
http://dx.doi.org/10.1016/s0167-4943(98)00133-2DOI Listing

Publication Analysis

Top Keywords

mortality rates
8
lower mortality
8
hypertensive patients
8
survival patients
8
patients
5
rates antihypertensive
4
antihypertensive therapy
4
therapy extreme
4
extreme age
4
age impact
4

Similar Publications

Background: The anti-melanoma differentiation-associated gene 5 (anti-MDA5) antibody-positive dermatomyositis is known for its association with rapidly progressive interstitial lung disease (RP-ILD) and ulcerative skin lesions, often presenting with or without muscle involvement. The aim of this study was to identify distinct clinical and laboratory features that could be used to evaluate disease progression in an ethnically diverse cohort of anti-MDA5 dermatomyositis patients at a U.S.

View Article and Find Full Text PDF

Background: Predicting burn-related mortality is vital for family counseling, triage, and resource allocation. Several of the burn-specific mortality prediction scores have been developed, including the Abbreviated Burn Severity Index (ABSI) in 1982. However, these scores are not tested for accuracy to support contemporary estimates of the global burden of burn injury.

View Article and Find Full Text PDF

Background: Pregnancy related hypertension is a leading cause of preventable maternal morbidity and mortality in the US, with consistently higher rates affecting racial minorities. Many complications are preventable with timely treatment, in alignment with the Alliance for Innovation on Maternal Health's Patient Safety Bundle ("Bundle"). The Bundle has been implemented successfully in inpatient settings, but 30% of preeclampsia-related morbidity occurs in outpatient settings in North Carolina.

View Article and Find Full Text PDF

Background: Patients supported by extracorporeal membrane oxygenation (ECMO) are at a high risk of brain injury, contributing to significant morbidity and mortality. This study aimed to employ machine learning (ML) techniques to predict brain injury in pediatric patients ECMO and identify key variables for future research.

Methods: Data from pediatric patients undergoing ECMO were collected from the Chinese Society of Extracorporeal Life Support (CSECLS) registry database and local hospitals.

View Article and Find Full Text PDF

Background: While existing risk calculators focus on mortality and complications, elderly patients are concerned with how operations will affect their quality of life, especially their independence. We sought to develop a novel clinically relevant and easy-to-use score to predict elderly patients' loss of independence after gastrointestinal surgery.

Methods: This retrospective cohort study included patients age ≥ 65 years enrolled in the American College of Surgeons National Surgical Quality Improvement Program database and Geriatric Pilot Project who underwent pancreatic, colorectal, or hepatic surgery (January 1, 2014- December 31, 2018).

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!