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Mitochondrial quality control: the real dawn of intervertebral disc degeneration?
J Transl Med
December 2024
Department of Orthopedics, Spine Surgery, Second Affiliated Hospital of Naval Medical University, Shanghai, 200003, China.
Intervertebral disc degeneration is the most common disease in chronic musculoskeletal diseases and the main cause of low back pain, which seriously endangers social health level and increases people's economic burden. Disc degeneration is characterized by NP cell apoptosis, extracellular matrix degradation and disc structure changes. It progresses with age and under the influence of mechanical overload, oxidative stress and genetics.
View Article and Find Full Text PDFGrand (meta) challenges in planetary health: environmental, social, and cognitive.
Front Public Health
December 2024
National Centre for Epidemiology and Population Health, Australian National University, Canberra, ACT, Australia.
The term "planetary health", coined in the 1970s, arose from planetary consciousness, stimulated in part by the dawn of the space age, and commensurate recognition that our species faces extraordinary obstacles ("limits to growth") if it is to fulfil its promise. While such awareness was then widely suppressed, awareness is reviving, driven by the now obvious perils, not only of climate change but also from weaponization and national aggression. Our neoliberal society (including in academic circles) has inappropriately rewarded articles and researchers that are biased toward optimism.
View Article and Find Full Text PDFFlow-diverting stents for the treatment of unruptured distal anterior cerebral artery aneurysms: analysis of the CRETA Registry.
J Neurointerv Surg
December 2024
UOSA Neuroradiologia Interventistica, Fondazione Policlinico Universitario Agostino Gemelli IRCCS Roma, Roma, Italy
Background: Data about the safety and the efficacy of flow diversion for distal anterior cerebral artery (DACA) aneurysms are limited. We present the largest multicenter analysis evaluating the outcomes of flow diversion in unruptured DACA aneurysm treatment.
Methods: Databases from 39 centers were retrospectively reviewed for unruptured DACA aneurysms treated with flow-diverting stents.
Associations between airborne algae, ambient air pollution and lung function in a cross-sectional canadian population-based study.
Environ Res
December 2024
Environmental Health Science & Research Bureau, Health Canada, Canada. Electronic address:
Airborne algae have been associated with respiratory illness in the setting of coastal harmful algae blooms but little is known about their effects in urban populations distributed across a country, and whether ambient air pollution is an effect modifier. Using cross-sectional data from 11,256 participants of the Canadian Health Measures Survey (CHMS), we tested the association between lung function expressed as a forced expiratory volume (FEV) and airborne concentrations of algae measured by a rotation impact sampler in the participant's city of residence on the day of spirometric testing. The daily upper 95th percentiles of algae ranged from 12.
View Article and Find Full Text PDFCurrent Perspectives for Treating Adolescents with Obesity and Type 2 Diabetes: A Review.
Nutrients
November 2024
Department of Pediatric Diabetes, Clinical Auxology and Obesity, Poznan University of Medical Sciences, 60-572 Poznan, Poland.
: Childhood obesity is an epidemic and a significant health concern all over the world. Several factors can influence excess weight gain, including eating behaviors, physical inactivity, and genetics. Children and adolescents with obesity have a four-times greater risk of developing type 2 diabetes (T2D) compared with their normal-weight peers.
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