In this study, the distribution of peroneal-nerve conduction velocity was studied in 17 normal subjects, using the collision method. Paired supramaximal stimuli with predetermined interstimulus intervals (ISI) were applied at distal and proximal points of peroneal nerve and the resultant compound muscle action potentials (CMAPs) were recorded. The change in CMAP amplitudes and areas with ISI were deduced, and the relative number of fibers corresponding to each conduction velocity group (CVG) were computed. Conduction velocities of the peroneal motor nerve innervating the Extensor Digitorum Brevis (EDB) muscle were found to be in the range of 28-52 m/s and CVG innervating the greatest number appears to be in 40-48 m/s range, which consists of 70% of all fibers. These results show that, compared with the median motor nerve, deep peroneal motor nerve that innervates the EDB muscle consist of slow fibers.
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http://dx.doi.org/10.1080/00207450490475977 | DOI Listing |
J Plast Reconstr Aesthet Surg
December 2024
Division of Plastic and Reconstructive Surgery, Rush University Medical Center, Chicago, IL, United States. Electronic address:
The timing of nerve blocks for amputation surgery with immediate targeted muscle reinnervation (TMR) has been disputed. Traditional practices often defer nerve blocks until post-amputation, fearing interference with motor nerve target identification for TMR. Here, we present a case series demonstrating that pre-amputation regional nerve blocks do not prevent the identification of motor nerve targets.
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January 2025
Division of Plastic and Reconstructive Surgery, Department of Surgery, University of Florida, Gainesville, FL.
Purpose: The branching pattern of the deep motor branch of the ulnar nerve (DBUN) in the hand is complex. The anatomy of the motor branch innervating the fourth lumbrical (4L), where paralysis results in a claw hand deformity after ulnar nerve injury, is not well defined. This cadaver study focused on mapping and defining anatomical landmarks in relation to the motor branch to the 4L.
View Article and Find Full Text PDFCerebellum
January 2025
Department of Psychological and Brain Sciences, Texas A&M University, College Station, TX, USA.
The cerebellum is involved in non-motor processing, supported by topographically distinct cerebellar activations and closed-loop circuits between the cerebellum and the cortex. Disruptions to cerebellar function may negatively impact prefrontal function and processing. Cerebellar resources may be important for offloading cortical processing, providing crucial scaffolding for normative performance and function.
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January 2025
Department of Physical Medicine and Rehabilitation, University of Missouri School of Medicine, Columbia, MO 65211, USA.
Amyotrophic Lateral Sclerosis (ALS) is a complex neurodegenerative disease primarily affecting motor neurons, leading to progressive muscle atrophy and paralysis. This review explores the role of Schwann cells in ALS pathogenesis, highlighting their influence on disease progression through mechanisms involving demyelination, neuroinflammation, and impaired synaptic function. While Schwann cells have been traditionally viewed as peripheral supportive cells, especially in motor neuron disease, recent evidence indicates that they play a significant role in ALS by impacting motor neuron survival and plasticity, influencing inflammatory responses, and altering myelination processes.
View Article and Find Full Text PDFHum Brain Mapp
January 2025
Department of Psychology, Concordia University, Montreal, Quebec, Canada.
The cortex and cerebellum are densely connected through reciprocal input/output projections that form segregated circuits. These circuits are shown to differentially connect anterior lobules of the cerebellum to sensorimotor regions, and lobules Crus I and II to prefrontal regions. This differential connectivity pattern leads to the hypothesis that individual differences in structure should be related, especially for connected regions.
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