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Excimer light versus excimer light plus trichloroacetic acid for vitiligo treatment: A comparative study.
Medicine (Baltimore)
March 2025
Department of Dermatology, Andrology and Venereology, Faculty of Medicine, Al-Azhar University, Cairo, Egypt.
Background: Vitiligo, a prevalent acquired depigmentation condition, involves a progressive melanocyte loss, posing significant treatment challenges. Excimer light has been employed in vitiligo treatment, while trichloroacetic acid (TCA) has been noted to induce chemical trauma, leading to perifollicular pigmentation and perilesional repigmentation in vitiligo. This study aims to assess and compare the efficacy and safety of using 308 nm monochromatic excimer light alone versus combining it with 50% TCA in treating vitiligo.
View Article and Find Full Text PDFPRELIMINARY VEGETATION-BASED EVALUATION OF SEMI-VOLATILE ORGANIC COMPOUNDS (SVOCs) USING PINE SPECIES: TOWARDS POLLUTION DATA COMPARABILITY.
Environ Pollut
March 2025
LEPABE-Laboratory for Process Engineering, Environment, Biotechnology and Energy, Faculty of Engineering, University of Porto, Rua Dr. Roberto Frias, 4200-465 Porto, Portugal; ALiCE - Associate Laboratory in Chemical Engineering, Faculty of Engineering, University of Porto, Rua Dr. Roberto Frias, 4200-465 Porto, Portugal. Electronic address:
Pine needles are suitable biomonitors of airborne semi-volatile organic compounds (SVOCs). However, the various pine species, each with unique distribution and ecological traits, may differ in their ability to retain pollutants. The SVOC uptake capacities between different vegetation species remain largely unknown, and this study seeks to address this gap.
View Article and Find Full Text PDFBioaccumulation of PCBs and OCPs in Antarctic phytoplankton and zooplankton: Insights into bioconcentration and biomagnification in Fildes Bay.
Sci Total Environ
March 2025
GEMA, Center for Genomics, Ecology & Environment, Universidad Mayor, Camino La Pirámide 5750, Huechuraba, Santiago, Chile; Dara Observatory Foundation, Santiago de Chile, Chile; Institute of Environment, Florida International University, University Park, Miami, FL 33199, USA. Electronic address:
This study was conducted at Fildes Bay, King George Island, Antarctica, from November 30th, 2019, to January 30th, 2020. We determined the concentrations of Organochlorine Pesticides (OCPs) and Polychlorinated Biphenyls (PCBs) in phytoplankton, and zooplankton. The most abundant compounds found were hexachlorobenzene (HCB) in phytoplankton and γ-HCH in zooplankton.
View Article and Find Full Text PDFNetwork Pharmacology and Experimental Verification: Phellodendri Chinensis Cortex-Cnidii Fructus Herb Pair Alleviates Atopic Dermatitis by Regulating the TLR4/NF-κB Pathway.
Drug Des Devel Ther
March 2025
College of Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan, People's Republic of China.
Background: Atopic Dermatitis (AD) is a common continuous inflammation dermatosis requiring efficacious therapeutic intervention. Phellodendri Chinensis Cortex-Cnidii Fructus (PC) herb pair has shown effectiveness and security in traditional Chinese medicine (TCM) clinical applications, yet its pharmacological constituents and mechanisms are not fully elucidated.
Purpose: This study used serum pharmacochemistry, network pharmacology, and validation experiments to examine the impact of PC in the treatment of AD.
Processing factors of pesticide residues in durum wheat milling fractions and pasta.
Food Chem
February 2025
ISS - Istituto Superiore di Sanità (National Institute of Health), Dept. Environment and Health - Viale Regina Elena, 299 - 00161 Roma, Italy. Electronic address:
A total of 242 processing factors (Pf) were determined for 34 pesticides studied in milling products (flour, semolina, bran, middlings, fine bran), in refined and wholemeal pasta. The durum wheat cv Platone was grown in the field and was treated with formulations containing acetamiprid, λ-cyhalothrin, deltamethrin, benzovindiflupyr, and prothioconazole, at dosages 5 times higher than the label. Part of the untreated wheat was fortified in the laboratory with a mixture of 31 pesticides (organophosphates, organochlorines, pyrethroids, and others) at spiking levels of 1.
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