AI Article Synopsis
- Latent TB infections are becoming more relevant in developed countries due to demographic and public health shifts, increasing the risk for certain groups.
- The current gold standard for diagnosing M. tuberculosis infection, the tuberculin skin test, has limitations and can yield false results, making careful administration crucial.
- The paper suggests implementing a pre-test risk assessment questionnaire and standardized evaluation criteria to improve TB testing accuracy based on international guidelines.
Article Abstract
Relevance of latent infection in the epidemiology of tuberculosis (TB) is expected to increase in many developed countries. Indeed, many demographic, social and public health changes could contribute to the expansion of groups or communities at significantly higher risk than the general population for infection to Mycobacterium tuberculosis or progression from latent to active disease. Tuberculin skin testing (TB), the gold standard for diagnosis of M. tuberculosis infection, is imperfect and prone to false positive and negative results, unless strictly targeted and carefully standardized for reliable performance and interpretation. This paper proposes a pre-test risk assessment questionnaire and standardized criteria for evaluation of TB test according to international guidelines.
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