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Histological evaluation of the regenerative potential of injectable hyaluronic acid hydrogel or collagen with blood clot as scaffolds during revascularization of immature necrotic dog's teeth.
Open Vet J
November 2024
Department of Basic Oral Medical Sciences, College of Dentistry, Qassim University, Buraydah, Saudi Arabia.
Background: Regenerative endodontics' primary objective is to establish a favorable environment in the root canal by removing infection, providing a sturdy scaffold, and sealing the apical end of the tooth tightly. These actions should promote pulp regeneration and root development.
Aim: This study evaluated histologically the regenerative potential of injectable hyaluronic acid (HA) hydrogel or collagen with blood clot as scaffolds during revascularization of immature necrotic dog's teeth.
Potential antiviral activity of rhamnocitrin against influenza virus H3N2 by inhibiting cGAS/STING pathway in vitro.
Sci Rep
November 2024
State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510180, China.
Article Synopsis
- Influenza poses a significant public health challenge, necessitating the urgent discovery of effective antiviral drugs, with rhamnocitrin—a lesser-studied flavonoid—showing promise against the virus.
- In laboratory tests with MDCK and A549 cells, rhamnocitrin demonstrated antiviral properties and prevented cell death from influenza virus A/Aichi/2/1968 (H3N2).
- Molecular studies indicated that rhamnocitrin binds well to proteins cGAS and STING, and inhibits the production of type I IFN and proinflammatory cytokines by blocking the cGAS/STING signaling pathway, suggesting its potential as an antiviral treatment.
It's not always histiocytic sarcoma: Immunocytochemistry to identify two unusual tumors in a Bernese Mountain dog.
Vet Clin Pathol
September 2024
Zoetis Reference Laboratories, Wheat Ridge, Colorado, USA.
A 7-year-old female spayed Bernese Mountain dog was presented for evaluation of hematuria. Incidentally, a right stifle sarcoma was diagnosed via cytology, which raised concern for histiocytic sarcoma (given the patient's signalment) versus another joint-associated sarcoma. Histopathology and immunohistochemistry revealed a CD18-negative, non-histiocytic origin cell population.
View Article and Find Full Text PDFKnowledge, attitudes, and practices of healthcare professionals regarding rabies in tertiary care hospitals: A cross-sectional study in Peshawar, Pakistan.
PLoS Negl Trop Dis
June 2024
Department of Biochemistry, Institute of Chemical and Life Science, Abdul Wali Khan University Mardan, Pakistan.
Background: Rabies, caused by the rhabdovirus, is a fatal zoonotic disease with over 59,000 annual deaths globally. Asia and Africa account for 95%, with India leading, followed by China. In Pakistan, where it's endemic, over 50,000 cases are reported yearly.
View Article and Find Full Text PDF"It's my calling", Canadian dog rescuers' motives and experiences for engaging in international dog rescue efforts.
PLoS One
May 2024
The Animal Welfare Program, Faculty of Land and Food Systems, University of British Columbia, British Columbia, Vancouver, Canada.
The importation of rescue dogs has become an increasingly common occurrence in recent years, often involving industrialized countries as the ultimate destination. However, international dog rescue activities have attracted considerable criticism from the veterinary community and the public due to the associated zoonotic disease and public health risks, as well as the potential poor behaviour of international rescue dogs. The Government of Canada has also recently placed a temporary suspension on all commercial dog imports from non-rabies free countries due to the growing concerns of the zoonotic disease risks.
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