Context: Hydatid cyst disease can occur in all viscera and soft tissues although the liver and the lungs are the most commonly involved organs. Pancreatic and breast involvement with the disease are extremely rare and the presence of this disease in these organs without any other organ involvement has not been previously reported.

Case Report: We present herein a patient with isolated pancreatic cyst hydatid treated successfully with complete cyst excision. However, 18 months after the pancreatic surgery, hydatid disease was found in the breast and again the cyst was completely removed. No other organ involvement has been detected during a 2-year follow-up.

Conclusions: Hydatid disease should be considered in the differential diagnosis of all cystic masses in all anatomic locations, especially in regions where the disease is endemic. The ideal treatment is the complete excision of the cyst without any spillage.

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