Hepatitis C virus (HCV) quasispeciation was studied in two children vertically coinfected with HCV and human immunodeficiency virus type 1 (HIV-1). HCV quasispecies diversification and liver injury were more significant in patient C1, who was immunocompetent with anti-HIV therapy, than in patient C2, who was immunosuppressed, in consistency with modulation of HCV quasispeciation and liver injury by immunocompetence in coinfected children.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC516277 | PMC |
| http://dx.doi.org/10.1128/JCM.42.9.4365-4369.2004 | DOI Listing |
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