In vitro susceptibilities of isolates of Sporothrix schenckii to itraconazole and terbinafine.

J Clin Microbiol

Departamento de Microbiologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Av. Antônio Carlos, 6627, 31270-901 Belo Horizonte, Minas Gerais, Brazil.

Published: September 2004

Thirty isolates of the yeast form of Sporothrix schenckii were evaluated for in vitro susceptibility to itraconazole and terbinafine by the recommended NCCLS modified technique (M27-A2). The MICs of itraconazole obtained oscillated between 0.062 and 4.0 microg/ml, and those of terbinafine oscillated between 0.007 and 0.50 microg/ml; therefore, terbinafine showed greater in vitro activity.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC516298PMC
http://dx.doi.org/10.1128/JCM.42.9.4319-4320.2004DOI Listing

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