Thirty isolates of the yeast form of Sporothrix schenckii were evaluated for in vitro susceptibility to itraconazole and terbinafine by the recommended NCCLS modified technique (M27-A2). The MICs of itraconazole obtained oscillated between 0.062 and 4.0 microg/ml, and those of terbinafine oscillated between 0.007 and 0.50 microg/ml; therefore, terbinafine showed greater in vitro activity.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC516298 | PMC |
http://dx.doi.org/10.1128/JCM.42.9.4319-4320.2004 | DOI Listing |
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