Method improvement: released cecal ligation-septic shock model.

Pathophysiology

Department of General Endocrine and Transplant Surgery, Medical University of Gdańsk, 7 Debinki Street, 80-952 Gdańsk, Poland.

Published: October 2004

A new released cecal ligation (RCL) technique of septic shock induction in rats is presented. It is relatively not complicated, fast, not expensive, and it mimics the human pathology. Presented procedure seems to be a useful alternative for the cecal ligation alone or cecal ligation and puncture to induce experimental septic shock in small laboratory animals.

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http://dx.doi.org/10.1016/j.pathophys.2004.06.005DOI Listing

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