AI Article Synopsis
- The study evaluates the thermodynamic and kinetic factors involved in the esterification of (S)-carnitine through calorimetric methods.
- The experiment utilizes a chemical system comprising acetic anhydride, nitric acid, and acetic acid, highlighting safety concerns linked to the explosive nature of nitric esters.
- It specifically examines adiabatic conditions, focusing on the impacts of batch adding acetic anhydride and starting the reaction at elevated temperatures.
Article Abstract
The present work aims at assessing both thermodynamic and kinetic parameters of the esterification process of the (S)-carnitine, using calorimetric techniques. The use of the system acetic anhydride/nitric acid/acetic acid as esterifying agent and the explosive behaviour of nitric esters lead to safety considerations that have been investigated by hypothesizing some common process deviations. In particular, it has been investigated in adiabatic conditions both the batch addition of acetic anhydride and the effect of an initial temperature higher than those required by the process.
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| http://dx.doi.org/10.1016/j.jhazmat.2004.04.020 | DOI Listing |
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