Glyphosate (N-[phosphonomethyl]glycine) is a nonselective herbicide used in agriculture as a foliage spray for the control and the destruction of herbaceous plants. Adverse skin reactions due to contact with this compound have been rarely described. We report a case of a 78-year-old woman presenting with extensive chemical burns on her trunk and legs caused by accidental contact with a glyphosate-surfactant formulation. The lesions healed in four weeks without scarring.
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http://dx.doi.org/10.1081/clt-120038769 | DOI Listing |
Am J Forensic Med Pathol
September 2012
Department of Forensic Medicine, Faculty of Medicine, Chiang Mai University, Thailand.
Glyphosate herbicide is promoted by the manufacturer as having no risks to human health, with acute toxicity being very low in normal use. In Thailand, however, poisoning from glyphosate agricultural herbicides has been increasing. A case of rapid lethal intoxication from glyphosate-surfactant herbicide involved a 37-year-old woman, who deliberately ingested approximately 500 mL of concentrated Roundup formulation (41% glyphosate as the isopropylamine salt and 15% polyoxyethylene amine; Mosanto Company).
View Article and Find Full Text PDFClin Toxicol (Phila)
December 2011
Nephrotoxicology, Internal Medicine, Soonchunhyang University Cheonan Hospital, Cheonan, Republic of Korea.
Background: Glyphosate, one of the most commonly used herbicides worldwide, has been considered as minimally toxic to humans. However, clinical toxicologists occasionally encounter cases of severe systemic toxicity. The purpose of this study was to determine the effect of glyphosate-surfactants ("glyphosate-surfactant toxicity") in patients with acute glyphosate intoxication.
View Article and Find Full Text PDFClin Toxicol (Phila)
August 2009
Graduate Institute of Clinical Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Introduction: Most of the glyphosate-surfactant herbicides (GlySH) are formulated commercial products containing isopropylamine (IPA) salt of glyphosate (IPAG), variable amount of a surfactant, and water. Although glyphosate is only slightly toxic to rats, ingestion of GlySH may lead to severe effects, including death, in humans. We conducted a study to evaluate the cardiovascular effects of the components of GlySH.
View Article and Find Full Text PDFClin Toxicol (Phila)
November 2008
Department of Emergency, Taichung Veterans General Hospital, Taichung, Taiwan, Republic of China.
Introduction: Glyphosate-surfactant herbicide (GlySH) is widely used as a non-selective herbicide. Most intoxicated cases are from ingestion, inhalation, and skin exposure. Intramuscular injection of GlySH has never been reported.
View Article and Find Full Text PDFCommun Agric Appl Biol Sci
April 2005
Universidad de Huelva, Departamento de Ciencias Agroforestales, Campus Universitario de La Rábida, 21819-Palos de la Frontera, Huelva (Spain).
The relationship between the spraying volume and glyphosate effectiveness has been widely studied over the years. Likewise, the effect of different adjuvants on glyphosate leaf adherence/penetration is currently well understood. However, not much is known about the way spraying volumes may influence these two herbicide properties or, in other words, which factor (adherence or penetration) is the limiting factor when spraying at low or high volumes of treatment.
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