Fusospirochetosis causing necrotic oral ulcers in patients with HIV infection.

Oral Surg Oral Med Oral Pathol Oral Radiol Endod

Division of Infectious Diseases, Elmhurst Hopsital Center, NY, USA.

Published: September 2004

Under certain permissive circumstances, normally occurring fusiform bacteria and Borrelia spirochetes can result in a symbiotic overgrowth that leads to necrotic oral ulcers (stomatitis), gingivitis, and periodontitis. These lesions are collectively known as oral fusospirochetosis and may be under-appreciated in patients with HIV infection and AIDS. Fusospirochetal oral ulcers in patients with HIV are often large, necrotic, and malodorous; they respond completely to penicillin. We report 3 patients with HIV infection and fusospirochetal ulcerative stomatitis and review the clinical presentation, microbiologic diagnosis, potential pathogenesis, and treatment of these lesions.

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http://dx.doi.org/10.1016/S1079210404002069DOI Listing

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