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A 1,3-Diaza-Claisen rearrangement that affords guanidines. | LitMetric

A 1,3-Diaza-Claisen rearrangement that affords guanidines.

Org Lett

Department of Chemistry, University of Vermont, Burlington, Vermont 05405, USA.

Published: September 2004

[reaction: see text] N-Alkyl-N'-tosylthioureas activated by EDCI react with azanorbonenes at room temperature through a 1,3-diaza-Claisen rearrangement, affording highly substituted, bicyclic guanidines in moderate to good yields.

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Source
http://dx.doi.org/10.1021/ol048575eDOI Listing

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text] n-alkyl-n'-tosylthioureas
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