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Predicting autoimmune thyroiditis in primary Sjogren's syndrome patients using a random forest classifier: a retrospective study.
Arthritis Res Ther
January 2025
Scientific Research Project Department, Guangdong Artificial Intelligence and Digital Economy Laboratory (Guangzhou), Pazhou Lab, Guangzhou, China.
Article Synopsis
- The study examines how effective machine learning, particularly the Random Forest Classifier, is in predicting thyroid-specific autoantibodies in patients with Primary Sjogren's syndrome (pSS) based on clinical data.
- A total of 96 pSS patients were analyzed through thyroid function tests to categorize them by the presence of autoantibodies, leading to the exploration of various risk factors using four different machine learning algorithms.
- The Random Forest Classifier yielded the best results (AUC = 0.755), highlighting age, IgG levels, complement C4, and dry mouth as significant predictors for autoimmune thyroiditis in these patients.
The immediate pain relief of low-level laser therapy for burning mouth syndrome: a retrospective study of 94 cases.
Front Oral Health
December 2024
Hospital of Stomatology, Sun Yat-sen University, Guangzhou, China.
Significance: Burning mouth syndrome (BMS) is a chronic orofacial pain disorder that seriously affects quality of life of patients. In recent years, Low-level laser therapy (LLLT) has been regarded as an important innovation in pain management, but there is insufficient evidence of its effectiveness in patients with painful BMS. This study aimed to evaluate the efficacy of LLLT for immediate pain relief due to BMS.
View Article and Find Full Text PDFIntraglandular botulinum toxin in postoperative head and neck fistula: a retrospective analysis.
Eur Arch Otorhinolaryngol
December 2024
Department of Otorhinolaryngology and Head- Neck Surgery, All India Institute of Medical Sciences, New Delhi, India.
Purpose: Orocervical (OCF) or pharyngocutaneous fistula (PCF) are one of the disastrous complications of head and neck cancer surgery. Conventional standards of management are predominantly conservative. Though a majority of such patients respond to conservative management, it nevertheless causes significant delay in wound healing.
View Article and Find Full Text PDFIntegrating oral health into primary care: a proof-of-concept for dry mouth management in the Australian community pharmacy setting.
Aust Dent J
December 2024
Australian Centre for Integration of Oral Health, School of Nursing and Midwifery, Western Sydney University, Penrith, New South Wales, Australia.
Background: Xerostomia (dry mouth) is a common yet severe problem, causing difficulty with eating, speaking, dental caries, and discomfort. Access issues to dental services, including cost and availability of dental practitioners, can delay timely diagnosis and management of dry mouth. Thus, there is a need for innovative approaches to manage xerostomia, involving non-dental primary care health practitioners.
View Article and Find Full Text PDFThe effect of smoking on Sjögren's disease development and severity: a comprehensive literature review.
Clin Exp Rheumatol
December 2024
Institute of Inflammation and Ageing, College of Medical and Dental Sciences, University of Birmingham, and National Institute of Health Research (NIHR) Birmingham Biomedical Research Centre and Department of Rheumatology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
Unlike other autoimmune diseases, little is known about the environmental risk factors for Sjögren's disease (SjD). Smoking is an important risk factor for rheumatoid arthritis but the relationship between smoking and SjD is more complex to understand. Current smoking seems to be negatively linked to SjD, whereas there is mixed data on past smoking.
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