Quantity determination of T- and B-leucocytes in peripheral blood in patients with candida induced subprosthetic stomatitis.

Introduction: The presence of pathological transformation of Candida species and especially of C. albicans is determined to a great degree by the status of humoral and especially of the cell-mediated immunity. The prosthetic stomatitis (Stomatitis subprothetica) and its development also depends on the immunological status of the organism.

Purpose: In the present study we have set as a purpose to define the quantity of B- and T-lymphocytes (T-early and T-late) in the peripheral blood in patients with subprosthetic stomatitis and isolated and proved C. albicans from the microbial prosthetic plate and the mucosa under the prosthesis.

Materials And Methods: We defined the quantity of the early and late E-rosette-forming T-lymphocytes by the method of Bach (1973) and The B-lymphocytes with complement receptors by the method of Mendes et al (1974) in 69 patients with subprosthetic stomatitis and in 33 people with plate prostheses without stomatitis

Results: In both of the studied groups an elevation of the early T-lymphocytes and lower values for the late E-rossette-forming T-lymphocytes compared to the normal values were found. The relative proportion of B-lymphocytes is insignificantly higher (p > 0.1) in the patients compared to the control group. The values of T- and B-lymphocytes vary in different directions and they must be interpreted individually.