We hypothesized that hyperbaric oxygenation (HBO) combined with a long tube (LT) [HBO + LT] would be more effective than HBO combined with a short tube (ST) [HBO + ST] for simple adhesive postoperative intestinal obstruction (APIO) in children, assuming that there is synergism between HBO and LT. The objective of this study was to determine retrospectively the effect of HBO + LT compared to HBO + ST for simple APIO in children. Seventy-three patients were diagnosed with simple APIO, and 51 of these patients were treated with HBO + LT during 104 HBO sessions, while 22 were treated with HBO + ST during 34 HBO sessions. HBO was performed at a pressure of 2 atmospheres for 60 minutes once daily. The recovery rates after HBO therapy were 87.5 % for the HBO + LT group and 82.4 % for the HBO + ST group (p = 0.4496). HBO was performed 5 +/- 3 (range 1 to 15) times for the HBO + LT group and 4 +/- 2 (range 1 to 8) times for the HBO + ST group (p = 0.9847) for ultimate recovery from simple APIO. The recovery rate after HBO therapy of up to 6 sessions was 78.2 % for HBO + LT and 92.1 % for HBO + ST (p = 0.0360) among the cases that recovered ultimately. The effect of HBO + LT did not significantly differ from that of HBO + ST, but the insertion of an LT is more intricate and the cost is higher than that of an ST. Therefore, we conclude that the use of an LT is not necessarily required for HBO therapy for simple APIO.
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http://dx.doi.org/10.1055/s-2004-820902 | DOI Listing |
Methods Mol Biol
January 2025
Bioprinting Laboratories Inc., Dallas, TX, USA.
Human brain organoids (HBOs) derived from pluripotent stem cells hold great potential for disease modeling and high-throughput compound screening, given their structural and functional resemblance to fetal brain tissues. These organoids can mimic early stages of brain development, offering a valuable in vitro model to study both normal and disordered neurodevelopment. However, current methods of generating HBOs are often low throughput and variable in organoid differentiation and involve lengthy, labor-intensive processes, limiting their broader application in both academic and industrial research.
View Article and Find Full Text PDFUndersea Hyperb Med
January 2025
King Hamad American Mission Hospital, A'ali, Kingdom of Bahrain.
Middle ear barotrauma (MEBT) is the most common complication in providing hyperbaric oxygen therapy (HBO). This study explored the impact of altering the shape of the time-pressure curve with the aim of reducing the occurrence of MEBT and optimizing the HBO experience during the pressurization process. Four distinct mathematically derived protocols-Constant Pressure Difference (CPD), Constant Volume Difference (CVD), Constant Ratio (CR), and Inverted Constant Ratio (ICR)-were investigated using computer simulations on a simple ear model.
View Article and Find Full Text PDFUndersea Hyperb Med
January 2025
Hansjorg Wyss Department of Plastic Surgery, NYU Grossman School of Medicine, New York, NY.
Introduction: When administering HBO , pressures can range from 1.4 atmospheres absolute (ATA) to 3 ATA. While different treatment profiles have been proposed, there is a paucity of literature comparing the effectiveness and risk profile associated with different pressures treating the same condition.
View Article and Find Full Text PDFUndersea Hyperb Med
January 2025
Graduate Program in Veterinary Medicine, Center of Rural Science, Federal University of Santa Maria (UFSM), Av. Roraima, 1000, building 42, room 3135, 97105-900 Santa Maria, RS, Brazil.
The assessment of rectal temperature and behavior is an important parameter in all patients for whom hyperbaric oxygen (HBO) therapy is used. The study aims to verify if there is less reduction in body temperature after HBO therapy in restless patients and their behavior during the therapeutic session. Clinical data from 217 HBO therapy sessions with 2 to 2,5 atmospheres absolute (ATA) were reviewed under therapy protocols of 30 (P1) or 45 (P2) minutes, covering 29 canines and 13 felines.
View Article and Find Full Text PDFUndersea Hyperb Med
January 2025
Department of Pathology, Faculty of Veterinary Medicine, Erciyes University, Kayseri, Turkey.
Background: Hyperbaric Oxygen Therapy (HBO) is a treatment modality that exposes patients to 100% oxygen at higher atmospheric pressures. Recently, HBO has emerged as a potential therapeutic option for various liver diseases, offering advantages such as improved tissue oxygenation, anti-inflammatory effects, enhanced wound healing, and potential hepatoprotective properties. Understanding the benefits of HBO in liver diseases can pave the way for novel therapeutic strategies and improved patient outcomes.
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