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Measles Among the Foreign-Born Population Residing in Spain, 2014-2022: Missed Opportunities for Vaccination.
Vaccines (Basel)
December 2024
National Centre for Epidemiology, Institute of Health Carlos III, 28029 Madrid, Spain.
Background/objectives: Spain has been in a measles elimination phase since 2014. No evidence exists about the distribution of measles cases among the population born outside Spain. The aim of this study was thus to describe the epidemiological situation of measles, stratified by place of birth, during the post-elimination period in Spain.
View Article and Find Full Text PDFMulticentric Study on the Diagnostic of Neuromuscular Diseases in Children with High Creatinine Phosphokinase Levels.
Children (Basel)
November 2024
Department of Neuropediatrics, Centro Materno-Infantil do Norte, Centro Hospitalar Universitário de Santo António (CHUdSA), Largo da Maternidade de Júlio Dinis 45, 4050-651 Porto, Portugal.
Background: Neuromuscular diseases (NMDs) are rare, predominantly hereditary, with progressive course disorders. Furthermore, diagnosis can be delayed by years after symptoms emerge, resulting in missed opportunities for modifying disease progression, specific therapeutic approaches, and counseling. Some NMDs have high levels of creatine phosphokinase (CK).
View Article and Find Full Text PDFLeveraging Leadership Development to Pre-Empt Leader Derailments.
Behav Sci (Basel)
November 2024
Psychology Department, Claremont McKenna College, Claremont, CA 91711, USA.
This article examines the role of leadership development interventions in pre-empting leader derailments. The research literature suggests that derailments are not only commonplace but associated with a range of significant costs, from financial, to mental health, to morale, to employee turnover, to missed opportunities. Given these costly consequences, this article seeks to answer the question: "Can leadership development-especially at early managerial-career stages and during transitions-play a significant role in mitigating leader derailments?" Research suggests that the majority of leadership failures occur-or are more visible-at senior organizational levels.
View Article and Find Full Text PDFEffect of psilocybin versus escitalopram on depression symptom severity in patients with moderate-to-severe major depressive disorder: observational 6-month follow-up of a phase 2, double-blind, randomised, controlled trial.
EClinicalMedicine
October 2024
Centre for Psychedelic Research, Division of Psychiatry, Department Brain Sciences, Imperial College London, United Kingdom.
Background: Psilocybin therapy (PT) produces rapid and persistent antidepressant effects in major depressive disorder (MDD). However, the long-term effects of PT have never been compared with gold-standard treatments for MDD such as pharmacotherapy or psychotherapy alone or in combination.
Methods: This is a 6-month follow-up study of a phase 2, double-blind, randomised, controlled trial involving patients with moderate-to-severe MDD.
Integration of gene expression and DNA methylation data using MLA-GNN for liver cancer biomarker mining.
Front Genet
December 2024
School of information engineering, Jingdezhen Ceramic University, Jingdezhen, China.
The early symptoms of hepatocellular carcinoma patients are often subtle and easily overlooked. By the time patients exhibit noticeable symptoms, the disease has typically progressed to middle or late stages, missing optimal treatment opportunities. Therefore, discovering biomarkers is essential for elucidating their functions for the early diagnosis and prevention.
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