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Different Mortality and Transfer Rates Between Teaching and Nonteaching Urban Hospitals Among Patients Presenting with Stevens-Johnson Syndrome.
Anaesth Crit Care Pain Med
March 2025
George Washington University School of Medicine and Health Sciences, 2300 I St NW, Washington, DC 20052.
Stevens-Johnson Syndrome is a rare disorder of the skin and mucous membranes accompanied by systemic symptoms that are life threatening and require immediate intervention. We sought to determine if different hospital types, specifically urban nonteaching hospitals versus urban teaching hospitals, have different outcomes among patients presenting with Stevens-Johnson Syndrome during hospitalization. Patients presenting to urban teaching and urban nonteaching hospitals were compared.
View Article and Find Full Text PDFDupilumab for Atopic Dermatitis-like Chronic Graft-versus-Host Disease in Three Pediatric Hematopoietic Cell Transplant Recipients.
J Pediatr Hematol Oncol
March 2025
Department of Pediatric Hematology/Oncology, Vanderbilt University Medical Center, Nashville, TN.
Atopic dermatitis (AD)-like graft-versus-host disease (GVHD) is a chronic form of skin GVHD with features that include erythema, xerosis, scaling, and pruritus. Patients often require treatment with systemic immunosuppression and aggressive topical therapies for relief. Long-term effects of chronic immunosuppression are undesirable and alternative therapies are needed.
View Article and Find Full Text PDFImplant Size Versus Mastectomy Weight in Breast Reconstruction: Does Matching Matter?
Ann Plast Surg
February 2025
From the Division of Plastic and Reconstructive Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA.
Introduction: During nipple-sparing mastectomy with direct-to-implant based breast reconstruction, if the size of the chosen implant is smaller than the mastectomy specimen, a volumetric mismatch occurs creating dead space. This study evaluates the effect of volumetric mismatch between chosen implant size and mastectomy weight on postoperative complications after breast reconstruction.
Methods: A multicenter retrospective cohort study was conducted on patients undergoing nipple-sparing mastectomy with direct-to-implant based breast reconstruction.
Recommendations on how to proceed in case of suspected allergy to penicillin/β-lactam antibiotics: Position paper of the German Society for Allergology and Clinical Immunology (DGAKI) in cooperation with the German Society for Pediatric Allergology (GPA), Austrian Society for Allergology and Immunology (ÖGAI) and the Swiss Society for Allergology and Immunology (SGAI).
Allergol Select
March 2025
Allergology and Immunology, Department of Dermatology, Venereology and Allergology, Charité-Universitätsmedizin Berlin, Berlin, Germany.
β-lactam antibiotics (BLAs) are still the antibiotics of first choice for the treatment of many bacterial infections. Treatment with a BLA is often hindered by a suspected allergy, up to 10% of the population report an allergy to penicillin. After allergological evaluation of the suspected allergic reaction to a BLA, most patients show a low probability of a BLA allergy; only in a minority of cases an allergic reaction to the repeated administration of a BLA appear likely in view of the previous history.
View Article and Find Full Text PDFCost-effectiveness analysis comparing QuantiFERON test and tuberculin skin test for the diagnosis of latent tuberculosis infection in immunocompetent children under 15 years of age in Colombia.
BMJ Open
March 2025
Departamento de Pediatría, Universidad de Antioquia, Medellin, Colombia.
Objective: To determine the cost-effectiveness of the QuantiFERON (QFT) test versus the tuberculin skin test (TST) in diagnosing latent tuberculosis infection (LTBI) in immunocompetent children under 15 years of age who are in contact with active tuberculosis (TB) patients in the context of the Colombian healthcare system.
Design: Health economic evaluation. Decision tree over a horizon of <1 year.
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